STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ML2070Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 69.7 kda protein Rv1836c SW:YI36_MYCTU (Q50597) fasta scores: E(): 0, 66.0% in 714 aa. (733 aa)    
Predicted Functional Partners:
ML2489
Possible secreted protein; Similar to Mycobacterium tuberculosis hypothetical 31.8 kda protein rv0383c or mtv036.18c TR:O53718 (EMBL:AL021931) fasta scores: E(): 0, 82.2% id in 286 aa. Contains a possible N-terminal signal sequence.
  
     0.768
ML1222
Conserved hypothetical protein; Identical to the previously sequenced Mycobacterium leprae hypothetical protein TR:Q49626 (EMBL:U00010) (198 aa); Fasta score E(): 0, 99.5% identity in 198 aa overlap. Highly similar to proteins of undefined function also found downstream of BioB orthologues in Mycobacterium tuberculosis Rv1591 TR:O06599 (EMBL:Z95586) (221 aa); Fasta score E(): 0, 63.8% identity in 188 aa overlap and Mycobacterium bovis BCG TR:O52590 (EMBL:AF041819) (193 aa); Fasta score E(): 0, 67.6% identity in 170 aa overlap.
  
     0.765
ML2321
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 36.5 kDa protein Rv3707c TR:O69675 (EMBL:AL022121) (336 aa) fasta scores: E(): 0, 81.6% id in 332 aa, and to Mycobacterium smegmatis hypothetical 35.9 kDa protein in asd 3'region SW:YASD_MYCSM (P41402) (333 aa) fasta scores: E(): 0, 70.8% id in 332 aa.
  
     0.764
ML2195
Probable exported protein; Similar to Mycobacterium tuberculosis hypothetical 28.6 kda protein TR:O53829 (EMBL:AL022004) fasta scores: E(): 0, 73.0% in 270 aa. Contains a possible N-terminal signal sequence.
  
     0.761
ML2529
Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0290 TR:O86362 (EMBL:AL021930) fasta scores: E(): 0, 76.4% id in 471 aa, and to Streptomyces coelicolor putative integral membrane protein SC3C3.21 TR:O86654 (EMBL:AL031231) fasta scores: E(): 1.9e-05, 23.8% id in 483 aa. Contains multiple possible membrane spanning hydrophobic domains towards the C-terminus.
  
     0.756
ML1720
Conserved hypothetical protein; Highly similar to Mycobacterium tuberculosis hypothetical protein RV3035 TR:O53282 (EMBL:AL021287) (360 aa); Fasta score E(): 0, 75.8% identity in 363 aa overlap.
  
    0.751
lpqF
Probale secreted protein; Similar to M. tuberculosis lipoprotein Rv3593 lpqF TR:O06155 (EMBL:Z95555) (452 aa); Fasta score E(): 0, 79.2% identity in 451 aa overlap, and weakly to several beta-lactamase proteins e.g. Xanthomonas maltophilia chromosomic class A beta-lactamase TR:Q9X5A7 (EMBL:AF123246) (304 aa); Fasta score E(): 0.019, 26.2% identity in 260 aa overlap.
  
     0.751
lpqB
Putative lipoprotein; Similar to Mycobacterium tuberculosis putative lipoprotein RV3244C OR MTCY20B11.19C TR:O05889 (EMBL:Z95121) fasta scores: E(): 0, 87.9% id in 579 aa, and to Streptomyces coelicolor putative lipoprotein SCE33.13C TR:CAB90922 (EMBL:AL355774) fasta scores: E(): 0.00039, 24.4% id in 624 aa. Contains a probable N-terminal signal sequence. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site.
  
     0.748
ML2581
Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0227C TR:P96409 (EMBL:Z92669) fasta scores: E(): 0, 76.6% id in 423 aa. Contains a possible N-terminal signal sequence and a possible membrane spanning hydrophobic domain.
  
     0.747
ML2596
Conserved membrane protein; Similar to Mycobacterium tuberculosis hypothetical protein RV0176 TR:O07420 (EMBL:Z97050) fasta scores: E(): 0, 54.9% id in 319 aa. Contains multiple possible membrane spanning hydrophobic domains.
 
    0.742
Your Current Organism:
Mycobacterium leprae
NCBI taxonomy Id: 272631
Other names: M. leprae TN, Mycobacterium leprae TN, Mycobacterium leprae str. TN, Mycobacterium leprae strain TN
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