Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ML2424 | ML2425 | gene:17576286 | gene:17576287 | Conserved hypothetical protein; Similar to several including: Mycobacterium tuberculosis phosphoserine phosphatase SerB Rv0505c SW:Y505_MYCTU (Q11169) (373 aa) fasta scores: E(): 0, 83.0% id in 306 aa. | Similar to Mycobacterium tuberculosis hypothetical protein Rv0504c SW:Y504_MYCTU (Q11168) (166 aa) fasta scores: E(): 0, 83.1% id in 166 aa; Similar to ML1908 and ML1910; Belongs to the UPF0336 family. | 0.737 |
| ML2424 | cmaA2 | gene:17576286 | gene:17576288 | Conserved hypothetical protein; Similar to several including: Mycobacterium tuberculosis phosphoserine phosphatase SerB Rv0505c SW:Y505_MYCTU (Q11169) (373 aa) fasta scores: E(): 0, 83.0% id in 306 aa. | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | 0.729 |
| ML2425 | ML2424 | gene:17576287 | gene:17576286 | Similar to Mycobacterium tuberculosis hypothetical protein Rv0504c SW:Y504_MYCTU (Q11168) (166 aa) fasta scores: E(): 0, 83.1% id in 166 aa; Similar to ML1908 and ML1910; Belongs to the UPF0336 family. | Conserved hypothetical protein; Similar to several including: Mycobacterium tuberculosis phosphoserine phosphatase SerB Rv0505c SW:Y505_MYCTU (Q11169) (373 aa) fasta scores: E(): 0, 83.0% id in 306 aa. | 0.737 |
| ML2425 | cmaA2 | gene:17576287 | gene:17576288 | Similar to Mycobacterium tuberculosis hypothetical protein Rv0504c SW:Y504_MYCTU (Q11168) (166 aa) fasta scores: E(): 0, 83.1% id in 166 aa; Similar to ML1908 and ML1910; Belongs to the UPF0336 family. | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | 0.852 |
| cmaA2 | ML2424 | gene:17576288 | gene:17576286 | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | Conserved hypothetical protein; Similar to several including: Mycobacterium tuberculosis phosphoserine phosphatase SerB Rv0505c SW:Y505_MYCTU (Q11169) (373 aa) fasta scores: E(): 0, 83.0% id in 306 aa. | 0.729 |
| cmaA2 | ML2425 | gene:17576288 | gene:17576287 | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | Similar to Mycobacterium tuberculosis hypothetical protein Rv0504c SW:Y504_MYCTU (Q11168) (166 aa) fasta scores: E(): 0, 83.1% id in 166 aa; Similar to ML1908 and ML1910; Belongs to the UPF0336 family. | 0.852 |
| cmaA2 | fabG1 | gene:17576288 | gene:17575654 | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | 3-oxoacyl-[ACP] reductase (aka MabA); Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa); Fasta score E(): 0, 47.3% identity in 241 aa overlap. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature; Simil [...] | 0.489 |
| cmaA2 | fadD32 | gene:17576288 | gene:17573912 | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv3801c, fadD32, putative acyl-CoA synthase, TR:O53580 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 93.2% identity in 632 aa overlap. Similar to Mycobacterium bovis BCG ORF3, acyl-CoA synthase, TR:P71495 (EMBL:U75685) (582 aa); Fasta score E(): 0, 36.8% identity in 581 aa overlap and to domains of polyketide synthases e.g. Myxococcus xanthus safB, saframycin Mx1 synthetase B, TR:Q50857 (EMBL:U24657) (1770 aa); Fasta score E(): 0, 36.4% identity in 605 aa overlap. Contains Pfam match to entry PF005 [...] | 0.503 |
| cmaA2 | kasA | gene:17576288 | gene:17575498 | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.406 |
| cmaA2 | kasB | gene:17576288 | gene:17575499 | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.464 |
| cmaA2 | pks13 | gene:17576288 | gene:17573913 | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | Similar to many polyketide synthases from M. tuberculosis e.g. ppsA, M. tuberculosis phenolpthiocerol synthesis polyketide synthase, SW:PPSA_MYCTU (Q10977) (1876 aa); Fasta score E(): 0, 36.1% identity in 1277 aa overlap. Similar to many others e.g. Streptomyces noursei nysI, nystatin biosynthesis polyketide synthase, TR:AAF71766 (EMBL:AF263912) (9477 aa); Fasta score E(): 0, 33.4% identity in 1215 aa overlap. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entr [...] | 0.538 |
| fabG1 | cmaA2 | gene:17575654 | gene:17576288 | 3-oxoacyl-[ACP] reductase (aka MabA); Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa); Fasta score E(): 0, 47.3% identity in 241 aa overlap. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature; Simil [...] | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | 0.489 |
| fabG1 | fadD32 | gene:17575654 | gene:17573912 | 3-oxoacyl-[ACP] reductase (aka MabA); Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa); Fasta score E(): 0, 47.3% identity in 241 aa overlap. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature; Simil [...] | Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv3801c, fadD32, putative acyl-CoA synthase, TR:O53580 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 93.2% identity in 632 aa overlap. Similar to Mycobacterium bovis BCG ORF3, acyl-CoA synthase, TR:P71495 (EMBL:U75685) (582 aa); Fasta score E(): 0, 36.8% identity in 581 aa overlap and to domains of polyketide synthases e.g. Myxococcus xanthus safB, saframycin Mx1 synthetase B, TR:Q50857 (EMBL:U24657) (1770 aa); Fasta score E(): 0, 36.4% identity in 605 aa overlap. Contains Pfam match to entry PF005 [...] | 0.515 |
| fabG1 | kasA | gene:17575654 | gene:17575498 | 3-oxoacyl-[ACP] reductase (aka MabA); Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa); Fasta score E(): 0, 47.3% identity in 241 aa overlap. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature; Simil [...] | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.928 |
| fabG1 | kasB | gene:17575654 | gene:17575499 | 3-oxoacyl-[ACP] reductase (aka MabA); Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa); Fasta score E(): 0, 47.3% identity in 241 aa overlap. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature; Simil [...] | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.919 |
| fabG1 | pks13 | gene:17575654 | gene:17573913 | 3-oxoacyl-[ACP] reductase (aka MabA); Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa); Fasta score E(): 0, 47.3% identity in 241 aa overlap. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature; Simil [...] | Similar to many polyketide synthases from M. tuberculosis e.g. ppsA, M. tuberculosis phenolpthiocerol synthesis polyketide synthase, SW:PPSA_MYCTU (Q10977) (1876 aa); Fasta score E(): 0, 36.1% identity in 1277 aa overlap. Similar to many others e.g. Streptomyces noursei nysI, nystatin biosynthesis polyketide synthase, TR:AAF71766 (EMBL:AF263912) (9477 aa); Fasta score E(): 0, 33.4% identity in 1215 aa overlap. Contains Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase. Contains Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain. Contains Pfam match to entr [...] | 0.671 |
| fadD32 | cmaA2 | gene:17573912 | gene:17576288 | Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv3801c, fadD32, putative acyl-CoA synthase, TR:O53580 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 93.2% identity in 632 aa overlap. Similar to Mycobacterium bovis BCG ORF3, acyl-CoA synthase, TR:P71495 (EMBL:U75685) (582 aa); Fasta score E(): 0, 36.8% identity in 581 aa overlap and to domains of polyketide synthases e.g. Myxococcus xanthus safB, saframycin Mx1 synthetase B, TR:Q50857 (EMBL:U24657) (1770 aa); Fasta score E(): 0, 36.4% identity in 605 aa overlap. Contains Pfam match to entry PF005 [...] | Cyclopropane mycolic acid synthase; Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L- methionine. In the absence of MmaA2, CmaA2 has a non-specific cis- cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid. Cyclopropanated mycolic acids are key factors participating in cell envelop [...] | 0.503 |
| fadD32 | fabG1 | gene:17573912 | gene:17575654 | Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv3801c, fadD32, putative acyl-CoA synthase, TR:O53580 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 93.2% identity in 632 aa overlap. Similar to Mycobacterium bovis BCG ORF3, acyl-CoA synthase, TR:P71495 (EMBL:U75685) (582 aa); Fasta score E(): 0, 36.8% identity in 581 aa overlap and to domains of polyketide synthases e.g. Myxococcus xanthus safB, saframycin Mx1 synthetase B, TR:Q50857 (EMBL:U24657) (1770 aa); Fasta score E(): 0, 36.4% identity in 605 aa overlap. Contains Pfam match to entry PF005 [...] | 3-oxoacyl-[ACP] reductase (aka MabA); Similar to M. tuberculosis fabG Rv1483 SW:FABG_MYCTU (Q48930) (247 aa); Fasta score E(): 0, 68.6% identity in 245 aa overlap, and to many others e.g. Escherichia coli fabG 3-oxoacyl-[acyl-carrier protein] reductase SW:FABG_ECOLI (P25716) (244 aa); Fasta score E(): 0, 47.3% identity in 241 aa overlap. Contains Pfam match to entry PF00678 adh_short_C2, Short chain dehydrogenase/reductase C-terminus. Contains Pfam match to entry PF00106 adh_short, short chain dehydrogenase. Contains PS00061 Short-chain dehydrogenases/reductases family signature; Simil [...] | 0.515 |
| fadD32 | kasA | gene:17573912 | gene:17575498 | Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv3801c, fadD32, putative acyl-CoA synthase, TR:O53580 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 93.2% identity in 632 aa overlap. Similar to Mycobacterium bovis BCG ORF3, acyl-CoA synthase, TR:P71495 (EMBL:U75685) (582 aa); Fasta score E(): 0, 36.8% identity in 581 aa overlap and to domains of polyketide synthases e.g. Myxococcus xanthus safB, saframycin Mx1 synthetase B, TR:Q50857 (EMBL:U24657) (1770 aa); Fasta score E(): 0, 36.4% identity in 605 aa overlap. Contains Pfam match to entry PF005 [...] | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.813 |
| fadD32 | kasB | gene:17573912 | gene:17575499 | Similar to several putative acyl-CoA synthases from M. tuberculosis e.g. M. tuberculosis Rv3801c, fadD32, putative acyl-CoA synthase, TR:O53580 (EMBL:AL123456) (637 aa); Fasta score E(): 0, 93.2% identity in 632 aa overlap. Similar to Mycobacterium bovis BCG ORF3, acyl-CoA synthase, TR:P71495 (EMBL:U75685) (582 aa); Fasta score E(): 0, 36.8% identity in 581 aa overlap and to domains of polyketide synthases e.g. Myxococcus xanthus safB, saframycin Mx1 synthetase B, TR:Q50857 (EMBL:U24657) (1770 aa); Fasta score E(): 0, 36.4% identity in 605 aa overlap. Contains Pfam match to entry PF005 [...] | 3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. | 0.828 |
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