STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (393 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase.
  
 
 0.999
pdhD
Dihydrolipoamide dehydrogenase.
  
  
 0.914
pdhC
Dihydrolipoamide S-acetyltransferase.
  
  
 0.786
pdhA
Pyruvate dehydrogenase (lipoamide), alpha chain; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
  
 0.748
pdhB
Pyruvate dehydrogenase (lipoamide), beta chain.
  
  
 0.713
kdtB
PANTETHEINE-PHOSPHATE ADENYLYLTRANSFERASE; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
     
 0.711
ptsG-2
PTS SYSTEM, GLUCOSE-SPECIFIC IIBC COMPONENT; Truncated.
  
  
 0.681
ptsI
PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
  
 
 0.637
ldh
D-LACTATE DEHYDROGENASE; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.615
lpp-5
Prolipoprotein.
  
    0.609
Your Current Organism:
Mycoplasma mycoides
NCBI taxonomy Id: 272632
Other names: M. mycoides subsp. mycoides SC str. PG1, Mycoplasma mycoides subsp. mycoides SC str. PG1, Mycoplasma mycoides subsp. mycoides SC strain PG1
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