STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiGlucose-6-phosphate isomerase. (427 aa)    
Predicted Functional Partners:
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.995
tpi
TRIOSEPHOSPHATE ISOMERASE; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.993
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.990
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.986
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.971
crr
PTS SYSTEM, GLUCOSE-SPECIFIC IIA COMPONENT.
    
 0.954
gap
Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.950
manB
Phosphoglucomutase or phosphomannomutase.
 
 
 0.950
ptsG-4
PTS system, glucose-specific, IIBC component.
    
 0.948
ptsG
PTS system, glucose-specific IIABC component.
    
 0.946
Your Current Organism:
Mycoplasma mycoides
NCBI taxonomy Id: 272632
Other names: M. mycoides subsp. mycoides SC str. PG1, Mycoplasma mycoides subsp. mycoides SC str. PG1, Mycoplasma mycoides subsp. mycoides SC strain PG1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.