STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPU_0540Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (222 aa)    
Predicted Functional Partners:
MYPU_0520
THYMIDYLATE KINASE (DTMP KINASE); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
    0.875
MYPU_0510
RECOMBINATION PROTEIN RECR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
      0.871
MYPU_0530
DNA POLYMERASE III SUBUNITS GAMMA AND TAU; Identified by sequence similarity; possible; similar to TREMBL:Q9X493 (Q9X493) Blastp2 P=3e-44 C=54%.
       0.837
MYPU_4720
DNA METHYLASE; Identified by sequence similarity; similar to SWISSPROT:P25201 (MTA1_ACICA) Blastp2 P=0.001 score=44 Pfscan: pos. 61-162 PS50193 | SAM_BIND SAM (and some other nucleotide) binding motif. pos. 134-140 PS00092 | N6_MTASE N-6 Adenine-specific DNA methylases signature.
 
    0.837
MYPU_0490
DNA POLYMERASE III SUBUNIT GAMMA AND TAU; Identified by sequence similarity; putative; similar to SWISS-PROT:P09122 (DP3X_BACSU) Blastp2 P=1e-71 C=26%.
       0.786
MYPU_0500
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
       0.786
MYPU_3520
SMALL PROTEIN B; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to tran [...]
     
 0.711
MYPU_3510
VACB-LIKE (Shigella flexneri) RIBONUCLEASE II; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
     
 0.691
MYPU_4930
METHYLTRANSFERASE; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
     
 0.688
MYPU_4940
Conserved hypothetical protein; Identified by sequence similarity; possible; similar to SWISS-PROT:O07319 (YLLB_STAAU) Blastp2 P=5e-19 C=50%; Belongs to the MraZ family.
      
 0.680
Your Current Organism:
Mycoplasma pulmonis
NCBI taxonomy Id: 272635
Other names: M. pulmonis UAB CTIP, Mycoplasma pulmonis UAB CTIP, Mycoplasma pulmonis str. UAB CTIP, Mycoplasma pulmonis strain UAB CTIP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.