STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPU_1450THYMIDINE KINASE; Identified by sequence similarity; possible; similar to SWISS-PROT:Q03221 (KITH_BACSU) Blastp2 P=2e-35 C=58%. (190 aa)    
Predicted Functional Partners:
MYPU_5380
THYMIDYLATE SYNTHASE (TS) (TSASE); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.961
MYPU_6450
PURINE NUCLEOSIDE PHOSPHORYLASE (INOSINE PHOSPHORYLASE) (PNP); Identified by sequence similarity; probable; similar to SWISS-PROT:P47295 (DEOD_MYCGE) Blastp2 P=3e-47 C=63%.
  
 
 0.942
MYPU_0520
THYMIDYLATE KINASE (DTMP KINASE); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
 
 0.941
MYPU_6460
THYMIDINE PHOSPHORYLASE (TDRPASE); Identified by sequence similarity; probable; similar to SWISS-PROT:P77836 (PDP_BACST) Blastp2 P=0 C=68%.
    
 0.934
MYPU_2780
DEOXYCYTIDYLATE DEAMINASE (DCMP DEAMINASE); Identified by sequence similarity; probable; similar to SWISS-PROT:P32321 (DCTD_HUMAN) Blastp2 P=5e-38 C=66%.
  
 
 0.930
MYPU_3790
CYTIDINE DEAMINASE (CYTIDINE AMINOHYDROLASE) (CDA); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.924
MYPU_0550
5'-NUCLEOTIDASE PRECURSOR; Identified by sequence similarity; putative; similar to SWISS-PROT:P22848 (5NTD_VIBPA) Blastp2 P=5e-36 C=42%; Belongs to the 5'-nucleotidase family.
    
  0.905
MYPU_1050
PEPTIDE CHAIN RELEASE FACTOR 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.797
MYPU_1440
POTASSIUM UPTAKE PROTEIN KTRB; Identified by sequence similarity; possible; similar to TREMBL:O67474 Blastp2 P=1e-19 score=131 Pfscan: pos. 154-161 PS00017 | ATP_GTP_A ATP/GTP-binding site motif A (P-loop).
       0.603
MYPU_6660
CTP SYNTHASE (UTP--AMMONIA LIGASE) (CTP SYNTHETASE); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.520
Your Current Organism:
Mycoplasma pulmonis
NCBI taxonomy Id: 272635
Other names: M. pulmonis UAB CTIP, Mycoplasma pulmonis UAB CTIP, Mycoplasma pulmonis str. UAB CTIP, Mycoplasma pulmonis strain UAB CTIP
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