STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYPU_4900METHIONYL-TRNA SYNTHETASE (METHIONINE--TRNA LIGASE) (METRS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (509 aa)    
Predicted Functional Partners:
MYPU_0930
LEUCYL-TRNA SYNTHETASE (LEUCINE--TRNA LIGASE); Identified by sequence similarity; probable; similar to SWISS-PROT:P36430 (SYL_BACSU) Blastp2 P=0 C=70%; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.997
MYPU_6820
GLUTAMYL-TRNA SYNTHETASE (GLUTAMATE--TRNA LIGASE) (GLURS); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
  
 0.992
MYPU_6670
ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE--TRNA LIGASE) (ILERS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
  
 0.989
MYPU_3480
Phenylalanine--tRNA ligase alpha subunit; Identified by sequence similarity; possible; similar to SWISS-PROT:P17921 (SYFA_BACSU) Blastp2 P=9e-58 C=57%; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
  
 
 0.988
MYPU_2430
ARGINYL-TRNA SYNTHETASE (ARGININE--TRNA LIGASE) (ARGRS); Identified by sequence similarity; possible; similar to SWISS-PROT:P46906 (SYR_BACSU) Blastp2 P=3e-97 C=52%; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.981
MYPU_7710
ASPARAGINYL-TRNA SYNTHETASE (ASPARAGINE--TRNA LIGASE) (ASNRS); Identified by sequence similarity; probable; similar to SWISS-PROT:O51128 (SYN_BORBU) Blastp2 P=0 C=70%.
  
 0.979
MYPU_1830
PROLYL-TRNA SYNTHETASE (PROLINE--TRNA LIGASE); Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 0.972
MYPU_3470
PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (PHENYLALANINE--TRNA LIGASE BETA CHAIN) (PHERS); Identified by sequence similarity; possible; similar to SWISS-PROT:P75563 (SYFB_MYCPN) Blastp2 P=3e-43 C=46%; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.972
MYPU_0450
METHIONYL-TRNA FORMYLTRANSFERASE; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
 
 0.948
MYPU_4850
TYROSYL-TRNA SYNTHETASE 1 (TYROSINE--TRNA LIGASE) (TYRRS 1); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
  
 
 0.903
Your Current Organism:
Mycoplasma pulmonis
NCBI taxonomy Id: 272635
Other names: M. pulmonis UAB CTIP, Mycoplasma pulmonis UAB CTIP, Mycoplasma pulmonis str. UAB CTIP, Mycoplasma pulmonis strain UAB CTIP
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.