node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
pur | purC | PM1053 | PM0815 | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | PurC; Belongs to the SAICAR synthetase family. | 0.602 |
pur | purD | PM1053 | PM0224 | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | PurD. | 0.963 |
pur | purE | PM1053 | PM0619 | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.963 |
pur | purF | PM1053 | PM0701 | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.698 |
pur | purH | PM1053 | PM0222 | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | PurH. | 0.974 |
pur | purK | PM1053 | PM0620 | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.623 |
pur | purL | PM1053 | PM1085 | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.996 |
pur | purM | PM1053 | PM0021 | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | PurM. | 0.773 |
pur | purN | PM1053 | PM0020 | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.957 |
purB | purC | PM1851 | PM0815 | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PurC; Belongs to the SAICAR synthetase family. | 0.989 |
purB | purD | PM1851 | PM0224 | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PurD. | 0.948 |
purB | purE | PM1851 | PM0619 | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.849 |
purB | purF | PM1851 | PM0701 | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.894 |
purB | purH | PM1851 | PM0222 | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PurH. | 0.994 |
purB | purK | PM1851 | PM0620 | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.865 |
purB | purL | PM1851 | PM1085 | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.989 |
purB | purM | PM1851 | PM0021 | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PurM. | 0.929 |
purB | purN | PM1851 | PM0020 | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.830 |
purC | pur | PM0815 | PM1053 | PurC; Belongs to the SAICAR synthetase family. | Pur; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.602 |
purC | purB | PM0815 | PM1851 | PurC; Belongs to the SAICAR synthetase family. | PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.989 |