STRINGSTRING
COQ2 protein (Naumovozyma castellii) - STRING interaction network
"COQ2" - 4-hydroxybenzoate polyprenyltransferase, mitochondrial in Naumovozyma castellii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COQ24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate (371 aa)    
Predicted Functional Partners:
XP_003678207.1
Uncharacterized protein; Ancestral locus Anc_3.202; Belongs to the FPP/GGPP synthase family (471 aa)
   
 
  0.987
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family (323 aa)
 
 
  0.956
COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3- polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6 (518 aa)
   
   
  0.945
XP_003676150.1
Uncharacterized protein; Ancestral locus Anc_6.36 (210 aa)
     
 
  0.940
XP_003676273.1
Uncharacterized protein; Ancestral locus Anc_6.133 (495 aa)
     
 
  0.929
COQ7
5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides (264 aa)
     
   
  0.926
XP_003676716.1
Uncharacterized protein; Ancestral locus Anc_7.351 (261 aa)
     
   
  0.925
COQ4
Ubiquinone biosynthesis protein NCAS0B02960, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family (334 aa)
           
  0.925
COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2) (297 aa)
     
   
  0.910
XP_003675470.1
Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O (390 aa)
   
   
  0.769
Your Current Organism:
Naumovozyma castellii
NCBI taxonomy Id: 27288
Other names: AS 2.2404, ATCC 76901, CBS 4309, CCRC 22586, DBVPG 6298, N. castellii, NRRL Y-12630, Naumovia castellii, Naumovozyma castellii, Naumovozyma castellii Kurtzman 2008, Saccharomyces castellii, Saccharomyces castellii Capriotti
Server load: low (25%) [HD]