STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crtEFarnesyltranstransferase; Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes. Belongs to the FPP/GGPP synthase family. (289 aa)    
Predicted Functional Partners:
crtB
Phytoene synthase; Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity). Belongs to the phytoene/squalene synthase family.
 
 0.993
crtF
Hydroxyneurosporene methyltransferase; Methyltransferase that mediates the O-methylation of 1- hydroxy carotenoids. Converts hydroxyneurosporene to methoxyneurosporene or demethylspheroidene to spheroidene. Also able to produce spirilloxanthin.
  
 0.989
bchP
Geranylgeranyl reductase; Catalyzes the stepwise hydrogenation of geranylgeraniol to phytol during bacteriochlorophyll A (BchlA) biosynthesis.
 
 0.987
idi1
Isopentenyl-diphosphate delta-isomerase-1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.975
idi2
Isopentenyl-diphosphate delta-isomerase-2; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.975
crtD
Methoxyneurosporene dehydrogenase; Catalyzes the introduction of C-3,4 double bonds into 1- hydroxyneurosporene (1-HO-Neu) to yield demethylspheroidene (DMS).
 
  
 0.955
uppS
Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.946
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
 
 0.942
ispA
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
  
0.937
bchC
2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; This protein catalyzes the penultimate step in bacteriochlorophyll a biosynthesis.
 
 
 0.936
Your Current Organism:
Rhodobacter capsulatus
NCBI taxonomy Id: 272942
Other names: R. capsulatus SB 1003, Rhodobacter capsulatus SB 1003
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.