STRINGSTRING
bioY protein (Rhodobacter capsulatus) - STRING interaction network
"bioY" - Biotin transporter BioY in Rhodobacter capsulatus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioYBiotin transporter BioY; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake (190 aa)    
Predicted Functional Partners:
cbiO3
Biotin transport ATP-binding protein BioM; Required for biotin uptake under very low (pM) biotin concentrations but not under higher (nM) concentrations (234 aa)
 
   
  0.999
cbiQ3
Energy-coupling factor transporter transmembrane protein BioN; Probably involved in biotin uptake, although complementation experiments in E.coli do not indicate a clear role (210 aa)
 
   
  0.999
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family (315 aa)
         
  0.835
bioD
ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (205 aa)
         
  0.798
bioF
annotation not available (377 aa)
         
  0.752
bioA
annotation not available (423 aa)
         
  0.736
dapA
4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta- semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (290 aa)
         
  0.702
birA1
annotation not available (242 aa)
 
     
  0.619
cydC
annotation not available (553 aa)
              0.593
cydD
annotation not available (581 aa)
              0.593
Your Current Organism:
Rhodobacter capsulatus
NCBI taxonomy Id: 272942
Other names: R. capsulatus SB 1003, Rhodobacter capsulatus, Rhodobacter capsulatus SB 1003
Server load: low (9%) [HD]