node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
bioF | bioY | RCAP_rcc03364 | RCAP_rcc03249 | 8-amino-7-oxononanoate synthase. | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | 0.778 |
bioF | cbiO3 | RCAP_rcc03364 | RCAP_rcc03251 | 8-amino-7-oxononanoate synthase. | Cobalt ABC transporter, ATP-binding protein CbiO-3; Required for biotin uptake under very low (pM) biotin concentrations but not under higher (nM) concentrations. | 0.612 |
bioF | cbiQ3 | RCAP_rcc03364 | RCAP_rcc03250 | 8-amino-7-oxononanoate synthase. | Cobalt ABC transporter, permease protein CbiQ-3; Probably involved in biotin uptake, although complementation experiments in E.coli do not indicate a clear role. | 0.651 |
bioF | dapA | RCAP_rcc03364 | RCAP_rcc00379 | 8-amino-7-oxononanoate synthase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.763 |
bioY | bioF | RCAP_rcc03249 | RCAP_rcc03364 | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | 8-amino-7-oxononanoate synthase. | 0.778 |
bioY | cbiO2 | RCAP_rcc03249 | RCAP_rcc02034 | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | Cobalt ABC transporter, ATP-binding protein CbiO-2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system. | 0.751 |
bioY | cbiO3 | RCAP_rcc03249 | RCAP_rcc03251 | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | Cobalt ABC transporter, ATP-binding protein CbiO-3; Required for biotin uptake under very low (pM) biotin concentrations but not under higher (nM) concentrations. | 0.999 |
bioY | cbiQ1 | RCAP_rcc03249 | RCAP_rcc01033 | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | Cobalt ABC transporter, permease protein CbiQ-1; Part of the energy-coupling factor (ECF) transporter complex NikMNQO involved in nickel import. The complex confers nickel uptake upon expression in E.coli; can also transport cobalt with a very low affinity. | 0.848 |
bioY | cbiQ2 | RCAP_rcc03249 | RCAP_rcc02035 | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | Cobalt ABC transporter, permease protein CbiQ-2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | 0.705 |
bioY | cbiQ3 | RCAP_rcc03249 | RCAP_rcc03250 | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | Cobalt ABC transporter, permease protein CbiQ-3; Probably involved in biotin uptake, although complementation experiments in E.coli do not indicate a clear role. | 0.999 |
bioY | cydC | RCAP_rcc03249 | RCAP_rcc03253 | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | Cysteine ABC transporter, permease/ATP-binding protein CydC. | 0.542 |
bioY | cydD | RCAP_rcc03249 | RCAP_rcc03252 | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | Cysteine ABC transporter, permease/ATP-binding protein CydD. | 0.552 |
bioY | dapA | RCAP_rcc03249 | RCAP_rcc00379 | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.652 |
cbiO2 | bioY | RCAP_rcc02034 | RCAP_rcc03249 | Cobalt ABC transporter, ATP-binding protein CbiO-2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system. | BioY family protein; Central protein that confers the ability to take up biotin on E.coli; while biotin transport requires BioM at very low (pM) concentrations at higher (nM) concentrations expression of BioY alone suffices for uptake. | 0.751 |
cbiO2 | cbiO3 | RCAP_rcc02034 | RCAP_rcc03251 | Cobalt ABC transporter, ATP-binding protein CbiO-2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system. | Cobalt ABC transporter, ATP-binding protein CbiO-3; Required for biotin uptake under very low (pM) biotin concentrations but not under higher (nM) concentrations. | 0.564 |
cbiO2 | cbiQ1 | RCAP_rcc02034 | RCAP_rcc01033 | Cobalt ABC transporter, ATP-binding protein CbiO-2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system. | Cobalt ABC transporter, permease protein CbiQ-1; Part of the energy-coupling factor (ECF) transporter complex NikMNQO involved in nickel import. The complex confers nickel uptake upon expression in E.coli; can also transport cobalt with a very low affinity. | 0.994 |
cbiO2 | cbiQ2 | RCAP_rcc02034 | RCAP_rcc02035 | Cobalt ABC transporter, ATP-binding protein CbiO-2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system. | Cobalt ABC transporter, permease protein CbiQ-2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity; Belongs to the CbiQ family. | 0.999 |
cbiO2 | cbiQ3 | RCAP_rcc02034 | RCAP_rcc03250 | Cobalt ABC transporter, ATP-binding protein CbiO-2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system. | Cobalt ABC transporter, permease protein CbiQ-3; Probably involved in biotin uptake, although complementation experiments in E.coli do not indicate a clear role. | 0.891 |
cbiO2 | cobL | RCAP_rcc02034 | RCAP_rcc02042 | Cobalt ABC transporter, ATP-binding protein CbiO-2; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. The complex confers cobalt uptake upon expression in E.coli; can also transport nickel with a very low affinity. Presumably responsible for energy coupling to the transport system. | precorrin-6Y C5,15-methyltransferase (decarboxylating). | 0.716 |
cbiO3 | bioF | RCAP_rcc03251 | RCAP_rcc03364 | Cobalt ABC transporter, ATP-binding protein CbiO-3; Required for biotin uptake under very low (pM) biotin concentrations but not under higher (nM) concentrations. | 8-amino-7-oxononanoate synthase. | 0.612 |