STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
crtBPhytoene synthase; Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity). Belongs to the phytoene/squalene synthase family. (355 aa)    
Predicted Functional Partners:
crtI
Phytoene dehydrogenase; Converts phytoene into all-trans-neurosporene as the major product, via the intermediary of phytofluene and zeta-carotene, by the introduction of three double bonds; Belongs to the carotenoid/retinoid oxidoreductase family.
 
 0.999
crtE
Farnesyl-diphosphate synthase; Catalyzes the condensation of farnesyl diphosphate (FPP) and isopentenyl diphosphate (IPP) to yield geranylgeranyl diphosphate (GGPP) needed for biosynthesis of carotenoids and diterpenes. Belongs to the FPP/GGPP synthase family.
 
 0.995
crtD
Methoxyneurosporene dehydrogenase; Catalyzes the introduction of C-3,4 double bonds into 1- hydroxyneurosporene (1-HO-Neu) to yield demethylspheroidene (DMS). It prefer the acyclic carotenoids such as 1-hydroxylycopene, and 1- hydroxy-gamma-carotene, whereas 1-hydroxy-3,4-didehydrolycopene and 1,1-dihydroxylycopene are much less effective.
  
 0.993
bchP
Geranylgeranyl hydrogenase; IMG reference gene:2512955284; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: geranylgeranyl reductase; geranylgeranyl reductase family.
 
 
 0.985
ispA
Geranylgeranyl pyrophosphate synthetase; IMG reference gene:2512956178; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.975
crtC
Hydroxyneurosporene dehydrogenase; Involved in the biosynthesis of carotenoids spheroidene and spirilloxanthin. Catalyzes the hydration of neurosporene to the corresponding hydroxylated carotenoids 1-HO-neurosporene and that of lycopene to 1-HO-lycopene (By similarity); Belongs to the CrtC hydratase family.
 
  
 0.968
RSP_0750
Geranylgeranyl pyrophosphate synthase/Polyprenyl synthetase; IMG reference gene:2512955775; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.964
crtA
Spheroidene monooxygenase; IMG reference gene:2512955279.
 
  
 0.958
tspO
TspO and MBR related proteins; IMG reference gene:2512955276; PFAM: TspO/MBR family.
 
  
 0.915
bchG
Chlorophyll synthase; Catalyzes the esterification of bacteriochlorophyllide a by geranylgeraniol-PPi.
 
  
 0.915
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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