node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HemH | RSP_6208 | RSP_1197 | RSP_6208 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.477 |
HemH | hemB | RSP_1197 | RSP_2848 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | IMG reference gene:2512954756; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.833 |
HemH | hemC | RSP_1197 | RSP_0679 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.797 |
HemH | hemE | RSP_1197 | RSP_0680 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.975 |
HemH | hemF | RSP_1197 | RSP_0682 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Coproporphyrinogen oxidase; IMG reference gene:2512955703; PFAM: Coproporphyrinogen III oxidase. | 0.911 |
HemH | hemN | RSP_1197 | RSP_0317 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Coproporphyrinogen III oxidase; Anaerobic transformation of coproporphyrinogen III into protoporphyrinogen IX. Dedicated to bacteriochlorophyll biosynthesis. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.779 |
HemH | hemZ | RSP_1197 | RSP_0699 | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the anaerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen III to yield the vinyl groups in protoporphyrinogen IX; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.776 |
RSP_1944 | RSP_6208 | RSP_1944 | RSP_6208 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512953857; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.936 |
RSP_1944 | cobA | RSP_1944 | RSP_2820 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512953857; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.915 |
RSP_1944 | hemB | RSP_1944 | RSP_2848 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512953857; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | IMG reference gene:2512954756; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.897 |
RSP_1944 | hemC | RSP_1944 | RSP_0679 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512953857; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.988 |
RSP_1944 | hemE | RSP_1944 | RSP_0680 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512953857; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.932 |
RSP_6208 | HemH | RSP_6208 | RSP_1197 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.477 |
RSP_6208 | RSP_1944 | RSP_6208 | RSP_1944 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512953857; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.936 |
RSP_6208 | cobA | RSP_6208 | RSP_2820 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.936 |
RSP_6208 | hemB | RSP_6208 | RSP_2848 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | IMG reference gene:2512954756; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.929 |
RSP_6208 | hemC | RSP_6208 | RSP_0679 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0.994 |
RSP_6208 | hemE | RSP_6208 | RSP_0680 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.942 |
RSP_6208 | hemF | RSP_6208 | RSP_0682 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Coproporphyrinogen oxidase; IMG reference gene:2512955703; PFAM: Coproporphyrinogen III oxidase. | 0.415 |
cobA | RSP_1944 | RSP_2820 | RSP_1944 | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512954789; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | uroporphyrinogen-III C-methyltransferase; IMG reference gene:2512953857; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.915 |