STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cbbLRibulose 1,5-bisphosphate carboxylase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (486 aa)    
Predicted Functional Partners:
cbbS
IMG reference gene:2512956326; PFAM: Ribulose bisphosphate carboxylase, small chain.
 
 0.999
prkA
Phosphoribulokinase; IMG reference gene:2512956329; PFAM: Phosphoribulokinase / Uridine kinase family.
 
 
 0.994
prkB
Phosphoribulokinase; IMG reference gene:2512956773; PFAM: Phosphoribulokinase / Uridine kinase family.
 
 
 0.988
cbbX
CbbX protein; IMG reference gene:2512956325; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; truncated by 32 aa.
 
  
 0.981
rbpL
Ribulose 1,5-bisphosphate carboxylase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type II subfamily.
  
 
0.958
cbbR
RuBisCO operon transcriptional regulator, CbbR; IMG reference gene:2512956331; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.
 
   
 0.955
cbbZ
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
  
 
 0.953
cfxA
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
  
 0.947
pgk
Phosphoglycerate kinase; IMG reference gene:2512954431; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
 
 0.919
gph
Phosphoglycolate phosphatase; IMG reference gene:2512954449; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; 2-phosphoglycolate phosphatase, prokaryotic.
    
 0.913
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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