STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prrAPrrA (RegA), Response regulator involved in oxygen regulation of photosynthesis genes; Member of the two-component regulatory system RegB/RegA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in response to a decrease in oxygen tension. (184 aa)    
Predicted Functional Partners:
prrB
Sensor histidine kinase PrrB (RegB); Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as well as in regulation of expression of genes involved in alternative CO2 fixation pathways. Phosphorylates RegA/PrrA.
 0.999
cbbR
RuBisCO operon transcriptional regulator, CbbR; IMG reference gene:2512956331; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain; Belongs to the LysR transcriptional regulatory family.
    
 
 0.950
prrC
PrrC; IMG reference gene:2512953414; PFAM: SCO1/SenC.
  
  
 0.950
ppsR
Transcriptional regulator, PpsR; IMG reference gene:2512955289; PFAM: Bacterial regulatory protein, Fis family; TIGRFAM: transcriptional regulator PpsR.
   
  
 0.829
appA
IMG reference gene:2512953460; PFAM: Sensors of blue-light using FAD.
   
  
 0.828
fnrL
Crp-Fnr regulatory protein (FnrL); Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes.
      
 0.827
hupT
Hydrogen uptake histidine-kinase; IMG reference gene:2512955502; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold.
     
 0.733
RSP_1056
Periplasmic sensor signal transduction histidine kinase; IMG reference gene:2512956097; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 
 0.702
RSP_6122
IMG reference gene:2512955649; PFAM: Protein of unknown function (DUF2948).
  
     0.695
nifA
NifA transcriptional activator; IMG reference gene:2512955560; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulatory protein.
  
  
 0.671
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.