STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (279 aa)    
Predicted Functional Partners:
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.999
coaX
Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
  
 
 0.968
RSP_1558
2-dehydropantoate 2-reductase; IMG reference gene:2512953455; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal.
  
 
 0.939
cmk
Cytidylate kinase; IMG reference gene:2512957104; PFAM: Cytidylate kinase; Adenylate kinase; TIGRFAM: cytidylate kinase.
 
    0.914
RSP_0599
Phosphopantothenoylcysteine synthase/decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.913
RSP_1507
Aldehyde dehydrogenase; IMG reference gene:2512953399; PFAM: Aldehyde dehydrogenase family.
   
 
 0.909
RSP_1292
IMG reference gene:2512956338; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
   
 
 0.908
RSP_3740
Aldehyde dehydrogenase; IMG reference gene:2512957273; PFAM: Aldehyde dehydrogenase family; Belongs to the aldehyde dehydrogenase family.
   
 
 0.902
RSP_2372
IMG reference gene:2512954312; PFAM: Aldehyde dehydrogenase family.
     
 0.901
truA
tRNA pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
     
 0.878
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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