node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSP_0169 | betB | RSP_0169 | RSP_2183 | Na+/solute symporter; IMG reference gene:2512955167; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.500 |
RSP_0169 | gltB | RSP_0169 | RSP_1146 | Na+/solute symporter; IMG reference gene:2512955167; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | Glutamine-pyruvate aminotransferase; IMG reference gene:2512956189; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 0.428 |
RSP_2185 | betA | RSP_2185 | RSP_2184 | Nuclease (SNase-like); IMG reference gene:2512954108; PFAM: Staphylococcal nuclease homologue; truncated by 12 aa. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.523 |
RSP_2185 | betB | RSP_2185 | RSP_2183 | Nuclease (SNase-like); IMG reference gene:2512954108; PFAM: Staphylococcal nuclease homologue; truncated by 12 aa. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.547 |
RSP_2185 | betI | RSP_2185 | RSP_2182 | Nuclease (SNase-like); IMG reference gene:2512954108; PFAM: Staphylococcal nuclease homologue; truncated by 12 aa. | Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. | 0.570 |
RSP_2185 | gltB | RSP_2185 | RSP_1146 | Nuclease (SNase-like); IMG reference gene:2512954108; PFAM: Staphylococcal nuclease homologue; truncated by 12 aa. | Glutamine-pyruvate aminotransferase; IMG reference gene:2512956189; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 0.552 |
RSP_2273 | betB | RSP_2273 | RSP_2183 | Putative anaerobic phenylacetate CoA ligase; IMG reference gene:2512954206. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.584 |
RSP_2339 | betB | RSP_2339 | RSP_2183 | Hypothetical protein; IMG reference gene:2512954275. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.577 |
betA | RSP_2185 | RSP_2184 | RSP_2185 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Nuclease (SNase-like); IMG reference gene:2512954108; PFAM: Staphylococcal nuclease homologue; truncated by 12 aa. | 0.523 |
betA | betB | RSP_2184 | RSP_2183 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.985 |
betA | betI | RSP_2184 | RSP_2182 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. | 0.920 |
betA | gltB | RSP_2184 | RSP_1146 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Glutamine-pyruvate aminotransferase; IMG reference gene:2512956189; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. | 0.402 |
betA | proV | RSP_2184 | RSP_2179 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | ABC glycine betaine/L-proline transporter, ATPase subunit, ProV; IMG reference gene:2512954102; PFAM: ABC transporter; TIGRFAM: choline ABC transporter, ATP-binding protein. | 0.548 |
betA | proX | RSP_2184 | RSP_2181 | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | IMG reference gene:2512954104; PFAM: Substrate binding domain of ABC-type glycine betaine transport system; TIGRFAM: choline ABC transporter, periplasmic binding protein. | 0.758 |
betB | RSP_0169 | RSP_2183 | RSP_0169 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Na+/solute symporter; IMG reference gene:2512955167; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.500 |
betB | RSP_2185 | RSP_2183 | RSP_2185 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Nuclease (SNase-like); IMG reference gene:2512954108; PFAM: Staphylococcal nuclease homologue; truncated by 12 aa. | 0.547 |
betB | RSP_2273 | RSP_2183 | RSP_2273 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Putative anaerobic phenylacetate CoA ligase; IMG reference gene:2512954206. | 0.584 |
betB | RSP_2339 | RSP_2183 | RSP_2339 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Hypothetical protein; IMG reference gene:2512954275. | 0.577 |
betB | betA | RSP_2183 | RSP_2184 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.985 |
betB | betI | RSP_2183 | RSP_2182 | Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Transcriptional regulator, TetR family; Repressor involved in choline regulation of the bet genes. | 0.929 |