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hisI protein (Rhodobacter sphaeroides 241) - STRING interaction network
"hisI" - Phosphoribosyl-AMP cyclohydrolase in Rhodobacter sphaeroides 241
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (119 aa)    
Predicted Functional Partners:
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; IMG reference gene-2512954173; PFAM- Histidine biosynthesis protein; TIGRFAM- phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (239 aa)
 
  0.999
hisE
IMG reference gene-2512954171; PFAM- Phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM- phosphoribosyl-ATP pyrophosphohydrolase (103 aa)
   
  0.999
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) (253 aa)
   
  0.997
hisB
IMG reference gene-2512954176; PFAM- Imidazoleglycerol-phosphate dehydratase (195 aa)
   
  0.991
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) (212 aa)
 
   
  0.972
hisD1
Histidinol dehydrogenase 1; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (434 aa)
 
   
  0.954
hisD
Putative histidinol dehydrogenase 2; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (441 aa)
 
   
  0.943
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily (236 aa)
 
   
  0.933
hisC
IMG reference gene-2512954218; PFAM- Aminotransferase class I and II; TIGRFAM- histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily (361 aa)
   
  0.930
RSP_1984
IMG reference gene-2512953900; PFAM- Aminotransferase class I and II; TIGRFAM- histidinol-phosphate aminotransferase; truncated by 14 aa (367 aa)
   
  0.884
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides 241, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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