node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSP_1365 | queA | RSP_1365 | RSP_2971 | Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.709 |
RSP_2970 | RSP_2972 | RSP_2970 | RSP_2972 | Transporter, Major facilitator superfamily (MFS); IMG reference gene:2512954936; PFAM: Sugar (and other) transporter; Major Facilitator Superfamily. | Hypothetical protein; IMG reference gene:2512954938. | 0.555 |
RSP_2970 | RSP_2973 | RSP_2970 | RSP_2973 | Transporter, Major facilitator superfamily (MFS); IMG reference gene:2512954936; PFAM: Sugar (and other) transporter; Major Facilitator Superfamily. | Peroxiredoxin; IMG reference gene:2512954939; PFAM: AhpC/TSA family. | 0.427 |
RSP_2970 | queA | RSP_2970 | RSP_2971 | Transporter, Major facilitator superfamily (MFS); IMG reference gene:2512954936; PFAM: Sugar (and other) transporter; Major Facilitator Superfamily. | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.695 |
RSP_2972 | RSP_2970 | RSP_2972 | RSP_2970 | Hypothetical protein; IMG reference gene:2512954938. | Transporter, Major facilitator superfamily (MFS); IMG reference gene:2512954936; PFAM: Sugar (and other) transporter; Major Facilitator Superfamily. | 0.555 |
RSP_2972 | RSP_2973 | RSP_2972 | RSP_2973 | Hypothetical protein; IMG reference gene:2512954938. | Peroxiredoxin; IMG reference gene:2512954939; PFAM: AhpC/TSA family. | 0.698 |
RSP_2972 | queA | RSP_2972 | RSP_2971 | Hypothetical protein; IMG reference gene:2512954938. | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.699 |
RSP_2973 | RSP_2970 | RSP_2973 | RSP_2970 | Peroxiredoxin; IMG reference gene:2512954939; PFAM: AhpC/TSA family. | Transporter, Major facilitator superfamily (MFS); IMG reference gene:2512954936; PFAM: Sugar (and other) transporter; Major Facilitator Superfamily. | 0.427 |
RSP_2973 | RSP_2972 | RSP_2973 | RSP_2972 | Peroxiredoxin; IMG reference gene:2512954939; PFAM: AhpC/TSA family. | Hypothetical protein; IMG reference gene:2512954938. | 0.698 |
RSP_2973 | queA | RSP_2973 | RSP_2971 | Peroxiredoxin; IMG reference gene:2512954939; PFAM: AhpC/TSA family. | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.695 |
gid | queA | RSP_2629 | RSP_2971 | Glucose-inhibited division protein A; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.803 |
queA | RSP_1365 | RSP_2971 | RSP_1365 | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Conserved hypothetical integral membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 0.709 |
queA | RSP_2970 | RSP_2971 | RSP_2970 | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Transporter, Major facilitator superfamily (MFS); IMG reference gene:2512954936; PFAM: Sugar (and other) transporter; Major Facilitator Superfamily. | 0.695 |
queA | RSP_2972 | RSP_2971 | RSP_2972 | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Hypothetical protein; IMG reference gene:2512954938. | 0.699 |
queA | RSP_2973 | RSP_2971 | RSP_2973 | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Peroxiredoxin; IMG reference gene:2512954939; PFAM: AhpC/TSA family. | 0.695 |
queA | gid | RSP_2971 | RSP_2629 | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Glucose-inhibited division protein A; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.803 |
queA | queG | RSP_2971 | RSP_1143 | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 4Fe-4S ferredoxin, iron-sulfur cluster binding protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.827 |
queA | ruvA | RSP_2971 | RSP_0555 | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Holliday junction DNA helicase subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.856 |
queA | ruvB | RSP_2971 | RSP_0553 | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Holliday junction DNA helicase subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.925 |
queA | tgt | RSP_2971 | RSP_2804 | S-adenosylmethionine tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] | 0.996 |