STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSP_3519Proline racemase; Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). Is involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate, which allows R.sphaeroides to grow on t4LHyp as a sole carbon source. Displays no proline racemase activity. (337 aa)    
Predicted Functional Partners:
RSP_0854
IMG reference gene:2512955884; PFAM: Ornithine cyclodeaminase/mu-crystallin family.
 
  
 0.994
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
 0.927
putA
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 0.910
pip
Prolyl aminopeptidase; IMG reference gene:2512956219; TIGRFAM: proline iminopeptidase, Neisseria-type subfamily; Belongs to the peptidase S33 family.
     
  0.900
ProS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
      
 0.879
tspO
TspO and MBR related proteins; IMG reference gene:2512955276; PFAM: TspO/MBR family.
   
    0.750
RSP_3515
ABC polyamine/opine transporter, periplasmic binding protein; IMG reference gene:2512957028; PFAM: Bacterial extracellular solute-binding protein.
 
     0.736
RSP_3518
ABC polyamine/opine transporter, inner membrane subunit; IMG reference gene:2512957031; PFAM: Binding-protein-dependent transport system inner membrane component.
 
    0.683
RSP_3656
IMG reference gene:2512957192; PFAM: Aldehyde dehydrogenase family.
 
 
 0.650
RSP_3516
ABC polyamine/opine transporter, ATPase subunit; IMG reference gene:2512957029; PFAM: ABC transporter; TOBE domain.
  
    0.644
Your Current Organism:
Rhodobacter sphaeroides 241
NCBI taxonomy Id: 272943
Other names: R. sphaeroides 2.4.1, Rhodobacter sphaeroides 2.4.1, Rhodobacter sphaeroides ATCC 17023, Rhodobacter sphaeroides ATH 2.4.1, Rhodobacter sphaeroides str. 2.4.1, Rhodobacter sphaeroides strain 2.4.1
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