RP109 protein (Rickettsia prowazekii) - STRING interaction network

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Score

RP109

PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb). (351 aa)

Predicted Functional Partners:

RP110

0.999

RP560

0.947

RP737

0.921

RP530

0.920

RP618

0.903

RP619

0.900

RP433

0.831

RP820

0.830

RP432

0.828

RP583

0.633

Your Current Organism:

Rickettsia prowazekii

NCBI taxonomy Id: 272947
Other names: R. prowazekii str. Madrid E, Rickettsia prowazekii str. Madrid E, Rickettsia prowazekii strain Madrid E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RP109	RP110	gene:17555192	gene:17555193	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	ACETATE KINASE (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	0.999
RP109	RP432	gene:17555192	gene:17555512	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	SUCCINYL-COA LIGASE (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.828
RP109	RP433	gene:17555192	gene:17555513	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	SUCCINYL-COA SYNTHETASE BETA CHAIN (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.831
RP109	RP530	gene:17555192	gene:17555610	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT (pdhC); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.920
RP109	RP560	gene:17555192	gene:17555640	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	PROBABLE 3-HYDROXYACYL-COA DEHYDROGENASE B0272.3 (fadB); In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.947
RP109	RP583	gene:17555192	gene:17555663	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	MAGNESIUM TRANSPORTER (mgtE); Acts as a magnesium transporter.	0.633
RP109	RP618	gene:17555192	gene:17555697	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	PROPIONYL-COA CARBOXYLASE ALPHA CHAIN PRECURSOR (pccA).	0.903
RP109	RP619	gene:17555192	gene:17555698	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	PROPIONYL-COA CARBOXYLASE BETA CHAIN PRECURSOR (pccB).	0.900
RP109	RP737	gene:17555192	gene:17555807	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	ACETYL-COA ACETYLTRANSFERASE (fadA); Belongs to the thiolase-like superfamily. Thiolase family.	0.921
RP109	RP820	gene:17555192	gene:17555889	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	POLY-BETA-HYDROXYBUTYRATE POLYMERASE (phbC2).	0.830
RP110	RP109	gene:17555193	gene:17555192	ACETATE KINASE (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	0.999
RP110	RP433	gene:17555193	gene:17555513	ACETATE KINASE (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	SUCCINYL-COA SYNTHETASE BETA CHAIN (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.428
RP110	RP560	gene:17555193	gene:17555640	ACETATE KINASE (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	PROBABLE 3-HYDROXYACYL-COA DEHYDROGENASE B0272.3 (fadB); In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.762
RP110	RP583	gene:17555193	gene:17555663	ACETATE KINASE (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	MAGNESIUM TRANSPORTER (mgtE); Acts as a magnesium transporter.	0.620
RP110	RP737	gene:17555193	gene:17555807	ACETATE KINASE (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	ACETYL-COA ACETYLTRANSFERASE (fadA); Belongs to the thiolase-like superfamily. Thiolase family.	0.442
RP110	RP820	gene:17555193	gene:17555889	ACETATE KINASE (ackA); Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.	POLY-BETA-HYDROXYBUTYRATE POLYMERASE (phbC2).	0.656
RP432	RP109	gene:17555512	gene:17555192	SUCCINYL-COA LIGASE (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	PROBABLE PHOSPHATE ACETYLTRANSFERASE (ptb).	0.828
RP432	RP433	gene:17555512	gene:17555513	SUCCINYL-COA LIGASE (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	SUCCINYL-COA SYNTHETASE BETA CHAIN (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.999
RP432	RP530	gene:17555512	gene:17555610	SUCCINYL-COA LIGASE (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT (pdhC); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).	0.960
RP432	RP560	gene:17555512	gene:17555640	SUCCINYL-COA LIGASE (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	PROBABLE 3-HYDROXYACYL-COA DEHYDROGENASE B0272.3 (fadB); In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.	0.772