node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RP044 | RP115 | gene:17555127 | gene:17555198 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | 0.929 |
RP044 | RP126 | gene:17555127 | gene:17555209 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT (sdhC); Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.999 |
RP044 | RP127 | gene:17555127 | gene:17555210 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | SUCCINATE DEHYDROGENASE HYDROPHOBIC MEMBRANE ANCHOR PROTEIN (sdhD); Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.998 |
RP044 | RP128 | gene:17555127 | gene:17555211 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT (sdhA). | 0.999 |
RP044 | RP179 | gene:17555127 | gene:17555262 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT (sucB); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.797 |
RP044 | RP180 | gene:17555127 | gene:17555263 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT (sucA); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.949 |
RP044 | RP432 | gene:17555127 | gene:17555512 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | SUCCINYL-COA LIGASE (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.993 |
RP044 | RP433 | gene:17555127 | gene:17555513 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | SUCCINYL-COA SYNTHETASE BETA CHAIN (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.990 |
RP044 | RP530 | gene:17555127 | gene:17555610 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT (pdhC); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.797 |
RP044 | RP801 | gene:17555127 | gene:17555870 | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | ATP SYNTHASE BETA CHAIN (atpD); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | 0.622 |
RP115 | RP044 | gene:17555198 | gene:17555127 | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.929 |
RP115 | RP126 | gene:17555198 | gene:17555209 | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT (sdhC); Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.731 |
RP115 | RP128 | gene:17555198 | gene:17555211 | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | SUCCINATE DEHYDROGENASE FLAVOPROTEIN SUBUNIT (sdhA). | 0.983 |
RP115 | RP179 | gene:17555198 | gene:17555262 | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT (sucB); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.849 |
RP115 | RP180 | gene:17555198 | gene:17555263 | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT (sucA); E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.884 |
RP115 | RP432 | gene:17555198 | gene:17555512 | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | SUCCINYL-COA LIGASE (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.911 |
RP115 | RP433 | gene:17555198 | gene:17555513 | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | SUCCINYL-COA SYNTHETASE BETA CHAIN (sucC); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.676 |
RP115 | RP530 | gene:17555198 | gene:17555610 | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT (pdhC); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | 0.617 |
RP115 | RP801 | gene:17555198 | gene:17555870 | NADH DEHYDROGENASE I CHAIN F (nuoF); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); Belongs to the complex I 51 kDa subunit family. | ATP SYNTHASE BETA CHAIN (atpD); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | 0.594 |
RP126 | RP044 | gene:17555209 | gene:17555127 | SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT (sdhC); Membrane-anchoring subunit of succinate dehydrogenase (SDH). | SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN (sdhB); Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.999 |