STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP562NITROGEN ASSIMILATION REGULATORY PROTEIN NTRX (ntrX); Member of the two-component regulatory system RP562/RP614. (475 aa)    
Predicted Functional Partners:
RP614
NITROGEN REGULATION PROTEIN NTRY (ntrY); Member of the two-component regulatory system RP614/RP562.
 
 0.987
RP465
ALKALINE PHOSPHATASE SYNTHESIS SENSOR PROTEIN PHOR (phoR).
 
 
 
 0.826
RP563
Unknown.
  
    0.784
RP229
HISTIDINE KINASE SENSOR PROTEIN (barA).
 
 
 0.768
RP335
Unknown.
  
 
 0.682
RP426
OSMOLARITY SENSOR PROTEIN ENVZ (envZ).
 
 
 0.636
RP816
DNAK SUPPRESSOR PROTEIN HOMOLOG (dksA); Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.
 
  
 0.625
RP495
Unknown; Belongs to the glutamine synthetase family.
  
  
 0.538
RP858
RNA POLYMERASE SIGMA FACTOR RPOD (rpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
 
   
 0.529
RP692
ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
 
 0.525
Your Current Organism:
Rickettsia prowazekii
NCBI taxonomy Id: 272947
Other names: R. prowazekii str. Madrid E, Rickettsia prowazekii str. Madrid E, Rickettsia prowazekii strain Madrid E
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