STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP661ELONGATION FACTOR TU (tuf); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa)    
Predicted Functional Partners:
RP039
30S RIBOSOMAL PROTEIN S6 (rpsF); Binds together with S18 to 16S ribosomal RNA.
  
 0.999
RP040
30S RIBOSOMAL PROTEIN S18 (rpsR); Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
  
 
 0.999
RP041
50S RIBOSOMAL PROTEIN L9 (rplI); Binds to the 23S rRNA.
  
 0.999
RP086
30S RIBOSOMAL PROTEIN S2 (rpsB); Belongs to the universal ribosomal protein uS2 family.
  
 0.999
RP087
ELONGATION FACTOR TS (tsf); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity); Belongs to the EF-Ts family.
  
 0.999
RP099
50S RIBOSOMAL PROTEIN L28 (rpmB); Belongs to the bacterial ribosomal protein bL28 family.
  
 
 0.999
RP100
50S RIBOSOMAL PROTEIN L31 (rpmE); Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
  
 
 0.999
RP112
50S RIBOSOMAL PROTEIN L19 (rplS); This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
 0.999
RP130
30S RIBOSOMAL PROTEIN S12 (rpsL); With S4 and S5 plays an important role in translational accuracy.
  
 0.999
RP131
30S RIBOSOMAL PROTEIN S7 (rpsG); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 0.999
Your Current Organism:
Rickettsia prowazekii
NCBI taxonomy Id: 272947
Other names: R. prowazekii str. Madrid E, Rickettsia prowazekii str. Madrid E, Rickettsia prowazekii strain Madrid E
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