node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RP055 | RP399 | gene:17555138 | gene:17555479 | NUCLEOSIDE DIPHOSPHATE KINASE (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.946 |
RP055 | RP505 | gene:17555138 | gene:17555585 | NUCLEOSIDE DIPHOSPHATE KINASE (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | KPSF PROTEIN (kpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.404 |
RP055 | RP512 | gene:17555138 | gene:17555592 | NUCLEOSIDE DIPHOSPHATE KINASE (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN (nrdB); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.924 |
RP055 | RP513 | gene:17555138 | gene:17555593 | NUCLEOSIDE DIPHOSPHATE KINASE (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE ALPHA CHAIN (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.929 |
RP055 | RP684 | gene:17555138 | gene:17555761 | NUCLEOSIDE DIPHOSPHATE KINASE (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | THYMIDYLATE KINASE (tmk); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.943 |
RP172 | RP513 | gene:17555255 | gene:17555593 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE ALPHA CHAIN (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.467 |
RP172 | RP684 | gene:17555255 | gene:17555761 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | THYMIDYLATE KINASE (tmk); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.856 |
RP172 | RP776 | gene:17555255 | gene:17555846 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.992 |
RP301 | RP399 | gene:17555382 | gene:17555479 | THY1 PROTEIN (thyA); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.951 |
RP301 | RP684 | gene:17555382 | gene:17555761 | THY1 PROTEIN (thyA); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | THYMIDYLATE KINASE (tmk); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.938 |
RP301 | RP776 | gene:17555382 | gene:17555846 | THY1 PROTEIN (thyA); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.546 |
RP399 | RP055 | gene:17555479 | gene:17555138 | DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | NUCLEOSIDE DIPHOSPHATE KINASE (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.946 |
RP399 | RP301 | gene:17555479 | gene:17555382 | DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | THY1 PROTEIN (thyA); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.951 |
RP399 | RP512 | gene:17555479 | gene:17555592 | DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN (nrdB); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.443 |
RP399 | RP513 | gene:17555479 | gene:17555593 | DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE ALPHA CHAIN (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.833 |
RP399 | RP684 | gene:17555479 | gene:17555761 | DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | THYMIDYLATE KINASE (tmk); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.959 |
RP399 | RP776 | gene:17555479 | gene:17555846 | DEOXYURIDINE 5-TRIPHOSPHATE NUCLEOTIDOHYDROLASE (dut); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.758 |
RP505 | RP055 | gene:17555585 | gene:17555138 | KPSF PROTEIN (kpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | NUCLEOSIDE DIPHOSPHATE KINASE (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.404 |
RP505 | RP684 | gene:17555585 | gene:17555761 | KPSF PROTEIN (kpsF); Belongs to the SIS family. GutQ/KpsF subfamily. | THYMIDYLATE KINASE (tmk); Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.737 |
RP512 | RP055 | gene:17555592 | gene:17555138 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN (nrdB); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | NUCLEOSIDE DIPHOSPHATE KINASE (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.924 |