STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP693RIBOSOMAL-PROTEIN-ALANINE ACETYLTRANSFERASE (rimJ). (183 aa)    
Predicted Functional Partners:
RP694
Unknown; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
     
 0.778
RP117
RIBONUCLEASE III (rnc); Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
  
    0.755
RP620
2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE (aas).
     
 0.727
RP373
MALIC ENZYME (tme); In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
     
 0.576
RP692
ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX (clpX); ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
       0.519
RP333
CAPD PROTEIN (capD); Epimerizes UDP-galactose to UDP-glucose. May contribute to formation of LPS or the exopolysaccharide slime layer by providing UDP- galactose as a substrate for either molecule.
     
 0.496
RP847
POSSIBLE PROTOPORPHYRINOGEN OXIDASE (hemK); Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; In the C-terminal section; belongs to the class I-like SAM- binding methyltransferase superfamily. TrmB family.
  
  
 0.470
RP335
Unknown.
  
  
 0.458
RP274
PEPTIDE CHAIN RELEASE FACTOR 2 (prfB); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
   
   0.429
Your Current Organism:
Rickettsia prowazekii
NCBI taxonomy Id: 272947
Other names: R. prowazekii str. Madrid E, Rickettsia prowazekii str. Madrid E, Rickettsia prowazekii strain Madrid E
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