STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RP739ADP,ATP CARRIER PROTEIN (tlc5); Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity); Belongs to the ADP/ATP translocase tlc family. (500 aa)    
Predicted Functional Partners:
RP403
Unknown.
      
 0.610
RP598
TRANSCRIPTION-REPAIR COUPLING FACTOR (mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the N-terminal section; belongs to the UvrB family.
      
 0.610
RP778
DNA POLYMERASE III, ALPHA CHAIN (dnaE); DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity); Belongs to the DNA polymerase type-C family. DnaE subfamily.
      
 0.610
RP884
PROBABLE FERROCHELATASE (hemH); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
      
 0.610
RP734
ATP-DEPENDENT NUCLEASE SUBUNIT A (addA).
      
 0.596
RP559
Unknown.
      
 0.587
Your Current Organism:
Rickettsia prowazekii
NCBI taxonomy Id: 272947
Other names: R. prowazekii str. Madrid E, Rickettsia prowazekii str. Madrid E, Rickettsia prowazekii strain Madrid E
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