node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RP007 | RP742 | gene:17555090 | gene:17555812 | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N- ACETYLGLUCOSAMINE O-ACYLTRANSFERASE (lpxA); Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | LIPOIC ACID SYNTHETASE (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.518 |
RP513 | RP742 | gene:17555593 | gene:17555812 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE ALPHA CHAIN (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | LIPOIC ACID SYNTHETASE (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.644 |
RP513 | RP776 | gene:17555593 | gene:17555846 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE ALPHA CHAIN (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.856 |
RP620 | RP741 | gene:17555699 | gene:17555811 | 2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE (aas). | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.866 |
RP620 | RP742 | gene:17555699 | gene:17555812 | 2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE (aas). | LIPOIC ACID SYNTHETASE (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.613 |
RP620 | RP743 | gene:17555699 | gene:17555813 | 2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE (aas). | SERINE HYDROXYMETHYLTRANSFERASE (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.712 |
RP620 | RP776 | gene:17555699 | gene:17555846 | 2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE (aas). | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.559 |
RP740 | RP741 | gene:17555810 | gene:17555811 | HEMOLYSIN C (tlyC). | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.882 |
RP740 | RP742 | gene:17555810 | gene:17555812 | HEMOLYSIN C (tlyC). | LIPOIC ACID SYNTHETASE (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.605 |
RP740 | RP743 | gene:17555810 | gene:17555813 | HEMOLYSIN C (tlyC). | SERINE HYDROXYMETHYLTRANSFERASE (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.604 |
RP740 | RP744 | gene:17555810 | gene:17555814 | HEMOLYSIN C (tlyC). | Unknown; Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. | 0.421 |
RP741 | RP620 | gene:17555811 | gene:17555699 | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE (aas). | 0.866 |
RP741 | RP740 | gene:17555811 | gene:17555810 | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | HEMOLYSIN C (tlyC). | 0.882 |
RP741 | RP742 | gene:17555811 | gene:17555812 | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | LIPOIC ACID SYNTHETASE (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.630 |
RP741 | RP743 | gene:17555811 | gene:17555813 | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | SERINE HYDROXYMETHYLTRANSFERASE (glyA); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.632 |
RP741 | RP744 | gene:17555811 | gene:17555814 | Unknown; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | Unknown; Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. | 0.438 |
RP742 | RP007 | gene:17555812 | gene:17555090 | LIPOIC ACID SYNTHETASE (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N- ACETYLGLUCOSAMINE O-ACYLTRANSFERASE (lpxA); Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.518 |
RP742 | RP513 | gene:17555812 | gene:17555593 | LIPOIC ACID SYNTHETASE (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE ALPHA CHAIN (nrdA); Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.644 |
RP742 | RP620 | gene:17555812 | gene:17555699 | LIPOIC ACID SYNTHETASE (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE (aas). | 0.613 |
RP742 | RP740 | gene:17555812 | gene:17555810 | LIPOIC ACID SYNTHETASE (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | HEMOLYSIN C (tlyC). | 0.605 |