node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RP172 | RP260 | gene:17555255 | gene:17555341 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | EXODEOXYRIBONUCLEASE III (xthA1). | 0.827 |
RP172 | RP326 | gene:17555255 | gene:17555406 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | DNA TOPOISOMERASE I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | 0.918 |
RP172 | RP335 | gene:17555255 | gene:17555415 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | Unknown. | 0.518 |
RP172 | RP419 | gene:17555255 | gene:17555499 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | DNA POLYMERASE III, BETA CHAIN (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiati [...] | 0.999 |
RP172 | RP676 | gene:17555255 | gene:17555753 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | EXODEOXYRIBONUCLEASE III (xthA2). | 0.827 |
RP172 | RP761 | gene:17555255 | gene:17555831 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | RECA PROTEIN (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.889 |
RP172 | RP776 | gene:17555255 | gene:17555846 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.992 |
RP172 | RP880 | gene:17555255 | gene:17555949 | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | DNA MISMATCH REPAIR PROTEIN MUTL (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | 0.588 |
RP260 | RP172 | gene:17555341 | gene:17555255 | EXODEOXYRIBONUCLEASE III (xthA1). | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | 0.827 |
RP260 | RP419 | gene:17555341 | gene:17555499 | EXODEOXYRIBONUCLEASE III (xthA1). | DNA POLYMERASE III, BETA CHAIN (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiati [...] | 0.927 |
RP260 | RP676 | gene:17555341 | gene:17555753 | EXODEOXYRIBONUCLEASE III (xthA1). | EXODEOXYRIBONUCLEASE III (xthA2). | 0.919 |
RP260 | RP761 | gene:17555341 | gene:17555831 | EXODEOXYRIBONUCLEASE III (xthA1). | RECA PROTEIN (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.401 |
RP260 | RP776 | gene:17555341 | gene:17555846 | EXODEOXYRIBONUCLEASE III (xthA1). | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.959 |
RP298 | RP326 | gene:17555379 | gene:17555406 | DNA MISMATCH REPAIR PROTEIN MUTS (mutS); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity). | DNA TOPOISOMERASE I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | 0.908 |
RP298 | RP419 | gene:17555379 | gene:17555499 | DNA MISMATCH REPAIR PROTEIN MUTS (mutS); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity). | DNA POLYMERASE III, BETA CHAIN (dnaN); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiati [...] | 0.993 |
RP298 | RP761 | gene:17555379 | gene:17555831 | DNA MISMATCH REPAIR PROTEIN MUTS (mutS); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity). | RECA PROTEIN (recA); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.752 |
RP298 | RP776 | gene:17555379 | gene:17555846 | DNA MISMATCH REPAIR PROTEIN MUTS (mutS); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity). | DNA POLYMERASE I (polA); In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.996 |
RP298 | RP880 | gene:17555379 | gene:17555949 | DNA MISMATCH REPAIR PROTEIN MUTS (mutS); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity). | DNA MISMATCH REPAIR PROTEIN MUTL (mutL); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity). | 0.999 |
RP326 | RP172 | gene:17555406 | gene:17555255 | DNA TOPOISOMERASE I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | DNA POLYMERASE III, DELTA SUBUNIT (holB); No ATG or GTG initiation codon found. ATA annotated as initiation codon. | 0.918 |
RP326 | RP298 | gene:17555406 | gene:17555379 | DNA TOPOISOMERASE I (topA); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing D [...] | DNA MISMATCH REPAIR PROTEIN MUTS (mutS); This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity). | 0.908 |