STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpS-1D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hpS-1); Energy Metabolism. (209 aa)    
Predicted Functional Partners:
hpS-2
D-arabino 3-hexulose 6-phosphate formaldehyde lyase (hpS-2); Similar to amino-end of most thermophilic homologues but same size as bacterial homologues. Carboxy-end seems to be upstream in distal SSO0151 orf; Energy Metabolism, Sugar metabolism.
 
 0.999
SSO2281
Conserved hypothetical protein; Involved in the synthesis of UDP-N-acetylgalactosamine (UDP- GalNAc). Catalyzes the conversion of glucosamine-6-phosphate (GlcN-6-P) to galactosamine-6-phosphate (GalN-6-P). Belongs to the PGI/PMI family.
    
 0.950
tkt-1
Transketolase, N-terminal section (tkt-1); Energy Metabolism, Sugar metabolism.
    
  0.902
tkt-2
Transketolase, C-terminal section (tkt-2); Energy Metabolism, Sugar metabolism.
    
  0.901
fbp
Conserved hypothetical protein; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
  0.900
gap
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) (gap); Can use both NAD and NADP as cofactors, but exhibits a marked preference for NADP; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
  
 0.797
cysH
3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) (cysH); Central Intermediary Metabolism, Sulfur.
     
 0.670
SSO0152
Hypothetical protein.
       0.665
kdgK
Fructokinase; Involved in the degradation of glucose and galactose via the semi-phosphorylative Entner-Doudoroff pathway. Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) and 2-keto-3- deoxygalactonate (KDGal) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxy-6-phosphogalactonate (KDPGal), respectively.
 
    0.578
rpiA
Ribose 5-phosphate isomerase (rpiA); Energy Metabolism.
 
   
 0.526
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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