node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SSO0241 | SSO0244 | SSO0241 | SSO0244 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Conserved hypothetical protein; Similar to PAB1091, PH0303, AF0654. | 0.700 |
SSO0241 | SSO1042 | SSO0241 | SSO1042 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Conserved hypothetical protein; Belongs to the UPF0201 family. | 0.569 |
SSO0241 | aroK | SSO0241 | SSO0308 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Conserved hypothetical protein; Similarity with AF0250, MJ1440, PAB0301, MTH805. Distantly related to homoserine/aspartokinases. | 0.550 |
SSO0241 | hisF | SSO0241 | SSO0597 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Imidazoleglycerol-phosphate synthase, cyclase subunit (hisF); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity). | 0.803 |
SSO0241 | hisH | SSO0241 | SSO0600 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Amidotransferase hisH (hisH); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity). | 0.803 |
SSO0241 | purA | SSO0241 | SSO0242 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Adenylosuccinate synthase (IMP--aspartate ligase) (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.789 |
SSO0241 | purB | SSO0241 | SSO0240 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Adenylosuccinate lyase (adenylosuccinase)(ASL) (purB); Purines; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.983 |
SSO0241 | purD | SSO0241 | SSO0635 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Phosphoribosylamine--glycine ligase (GAR synthetase) (GARS) (purD); Purines; Belongs to the GARS family. | 0.557 |
SSO0241 | purM | SSO0241 | SSO0636 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Phosphoribosylformylglycinamidine cyclo-ligase (AIR synthetase) (AIRS) (purM); Purines. | 0.529 |
SSO0241 | purP | SSO0241 | SSO0239 | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | Conserved hypothetical protein; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. Belongs to the phosphohexose mutase family. | 0.985 |
SSO0244 | SSO0241 | SSO0244 | SSO0241 | Conserved hypothetical protein; Similar to PAB1091, PH0303, AF0654. | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | 0.700 |
SSO0244 | purA | SSO0244 | SSO0242 | Conserved hypothetical protein; Similar to PAB1091, PH0303, AF0654. | Adenylosuccinate synthase (IMP--aspartate ligase) (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.852 |
SSO0244 | purB | SSO0244 | SSO0240 | Conserved hypothetical protein; Similar to PAB1091, PH0303, AF0654. | Adenylosuccinate lyase (adenylosuccinase)(ASL) (purB); Purines; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.607 |
SSO0244 | purP | SSO0244 | SSO0239 | Conserved hypothetical protein; Similar to PAB1091, PH0303, AF0654. | Conserved hypothetical protein; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. Belongs to the phosphohexose mutase family. | 0.697 |
SSO1042 | SSO0241 | SSO1042 | SSO0241 | Conserved hypothetical protein; Belongs to the UPF0201 family. | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | 0.569 |
SSO1042 | aroK | SSO1042 | SSO0308 | Conserved hypothetical protein; Belongs to the UPF0201 family. | Conserved hypothetical protein; Similarity with AF0250, MJ1440, PAB0301, MTH805. Distantly related to homoserine/aspartokinases. | 0.486 |
SSO1042 | purP | SSO1042 | SSO0239 | Conserved hypothetical protein; Belongs to the UPF0201 family. | Conserved hypothetical protein; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. Belongs to the phosphohexose mutase family. | 0.560 |
aroK | SSO0241 | SSO0308 | SSO0241 | Conserved hypothetical protein; Similarity with AF0250, MJ1440, PAB0301, MTH805. Distantly related to homoserine/aspartokinases. | Conserved hypothetical protein; Similar to PAB1272, PH0324, MJ0136, MTH1201,AF0256. | 0.550 |
aroK | SSO1042 | SSO0308 | SSO1042 | Conserved hypothetical protein; Similarity with AF0250, MJ1440, PAB0301, MTH805. Distantly related to homoserine/aspartokinases. | Conserved hypothetical protein; Belongs to the UPF0201 family. | 0.486 |
aroK | purP | SSO0308 | SSO0239 | Conserved hypothetical protein; Similarity with AF0250, MJ1440, PAB0301, MTH805. Distantly related to homoserine/aspartokinases. | Conserved hypothetical protein; Catalyzes the ATP- and formate-dependent formylation of 5- aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates. Belongs to the phosphohexose mutase family. | 0.537 |