node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MBP-like | SSO0264 | SSO0270 | SSO0264 | Multiprotein Bridging Factor (MBP-like), putative (MBP-like); Similar to APE2011, PH0783, AF1977, MTH729, PAB0842, Ta0948, MJ0586; Transcription. | Conserved hypothetical protein; Similarity with MJ119, APE2001. | 0.755 |
MBP-like | SSO0265 | SSO0270 | SSO0265 | Multiprotein Bridging Factor (MBP-like), putative (MBP-like); Similar to APE2011, PH0783, AF1977, MTH729, PAB0842, Ta0948, MJ0586; Transcription. | DNA modification methylase, type II R/M system; Cytosine-specific methyltransferase; Replication and Repair; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.755 |
MBP-like | SSO0267 | SSO0270 | SSO0267 | Multiprotein Bridging Factor (MBP-like), putative (MBP-like); Similar to APE2011, PH0783, AF1977, MTH729, PAB0842, Ta0948, MJ0586; Transcription. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.833 |
MBP-like | SSO0921 | SSO0270 | SSO0921 | Multiprotein Bridging Factor (MBP-like), putative (MBP-like); Similar to APE2011, PH0783, AF1977, MTH729, PAB0842, Ta0948, MJ0586; Transcription. | Conserved hypothetical protein; Conserved in archaea. | 0.453 |
MBP-like | hflX | SSO0270 | SSO0269 | Multiprotein Bridging Factor (MBP-like), putative (MBP-like); Similar to APE2011, PH0783, AF1977, MTH729, PAB0842, Ta0948, MJ0586; Transcription. | GTP-binding protein (hflX); GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Specific for GTP; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.885 |
MBP-like | pan | SSO0270 | SSO0271 | Multiprotein Bridging Factor (MBP-like), putative (MBP-like); Similar to APE2011, PH0783, AF1977, MTH729, PAB0842, Ta0948, MJ0586; Transcription. | AAA family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome as [...] | 0.806 |
MBP-like | tfE | SSO0270 | SSO0266 | Multiprotein Bridging Factor (MBP-like), putative (MBP-like); Similar to APE2011, PH0783, AF1977, MTH729, PAB0842, Ta0948, MJ0586; Transcription. | Transcription Factor E (TFE), TFIIE alpha subunit homolog (tfE); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and d [...] | 0.893 |
SSO0255 | SSO0267 | SSO0255 | SSO0267 | Nicotinamide mononucleotide adenylyltransferase, putative; Amino-end extention is missing compared to other homologues; Cofactor Biosynthesis, Pyridine nucleotides. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.760 |
SSO0255 | SSO0416 | SSO0255 | SSO0416 | Nicotinamide mononucleotide adenylyltransferase, putative; Amino-end extention is missing compared to other homologues; Cofactor Biosynthesis, Pyridine nucleotides. | Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). | 0.671 |
SSO0255 | tfE | SSO0255 | SSO0266 | Nicotinamide mononucleotide adenylyltransferase, putative; Amino-end extention is missing compared to other homologues; Cofactor Biosynthesis, Pyridine nucleotides. | Transcription Factor E (TFE), TFIIE alpha subunit homolog (tfE); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and d [...] | 0.485 |
SSO0255 | tiaS | SSO0255 | SSO0258 | Nicotinamide mononucleotide adenylyltransferase, putative; Amino-end extention is missing compared to other homologues; Cofactor Biosynthesis, Pyridine nucleotides. | Conserved hypothetical protein; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.675 |
SSO0264 | MBP-like | SSO0264 | SSO0270 | Conserved hypothetical protein; Similarity with MJ119, APE2001. | Multiprotein Bridging Factor (MBP-like), putative (MBP-like); Similar to APE2011, PH0783, AF1977, MTH729, PAB0842, Ta0948, MJ0586; Transcription. | 0.755 |
SSO0264 | SSO0265 | SSO0264 | SSO0265 | Conserved hypothetical protein; Similarity with MJ119, APE2001. | DNA modification methylase, type II R/M system; Cytosine-specific methyltransferase; Replication and Repair; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.852 |
SSO0264 | SSO0267 | SSO0264 | SSO0267 | Conserved hypothetical protein; Similarity with MJ119, APE2001. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.852 |
SSO0264 | hflX | SSO0264 | SSO0269 | Conserved hypothetical protein; Similarity with MJ119, APE2001. | GTP-binding protein (hflX); GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Specific for GTP; Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.755 |
SSO0264 | pan | SSO0264 | SSO0271 | Conserved hypothetical protein; Similarity with MJ119, APE2001. | AAA family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome as [...] | 0.578 |
SSO0264 | tfE | SSO0264 | SSO0266 | Conserved hypothetical protein; Similarity with MJ119, APE2001. | Transcription Factor E (TFE), TFIIE alpha subunit homolog (tfE); Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and d [...] | 0.852 |
SSO0265 | MBP-like | SSO0265 | SSO0270 | DNA modification methylase, type II R/M system; Cytosine-specific methyltransferase; Replication and Repair; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Multiprotein Bridging Factor (MBP-like), putative (MBP-like); Similar to APE2011, PH0783, AF1977, MTH729, PAB0842, Ta0948, MJ0586; Transcription. | 0.755 |
SSO0265 | SSO0264 | SSO0265 | SSO0264 | DNA modification methylase, type II R/M system; Cytosine-specific methyltransferase; Replication and Repair; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Conserved hypothetical protein; Similarity with MJ119, APE2001. | 0.852 |
SSO0265 | SSO0267 | SSO0265 | SSO0267 | DNA modification methylase, type II R/M system; Cytosine-specific methyltransferase; Replication and Repair; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Conserved hypothetical protein; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. | 0.852 |