STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gch3Conserved hypothetical protein; Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity; Belongs to the archaeal-type GTP cyclohydrolase family. (231 aa)    
Predicted Functional Partners:
trzA-like
Close hit to N ethylammeline chlorohydrolase related protein; Cellular Processes.
       0.852
ribH
Riboflavin synthase beta chain (6,7 dimethyl 8-ribityllumazine synthase) (DMRKL synthase) (ribH); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
       0.852
ribC
Riboflavin synthase (ribC); Cofactor Biosynthesis, Riboflavin.
       0.852
ribA
GTP Cyclohydrolase II (3,4-Dihydroxy-2-Butanone 4- Phosphate Synthase (DHBP synthase) (ribA); Cofactor Biosynthesis, Riboflavin.
       0.852
ndk
Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.800
cyaB
Adenylate cyclase, cyaB-type, putative (cyaB); Cellular Processes, Purines.
     
  0.800
pyK
Pyruvate kinase (pyK); Energy Metabolism, Glycolysis; Belongs to the pyruvate kinase family.
     
  0.800
SSO0403
Conserved hypothetical protein.
       0.563
SSO2832
Conserved hypothetical protein.
     
 0.413
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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