node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SSO0432 | SSO0433 | SSO0432 | SSO0433 | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | O-sialoglycoprotein endopeptidase; Protein modification. | 0.861 |
SSO0432 | kae1 | SSO0432 | SSO0434 | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | 0.861 |
SSO0432 | rps24E | SSO0432 | SSO0435 | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | SSU ribosomal protein S24E (rps24E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.652 |
SSO0432 | rps27AE | SSO0432 | SSO5844 | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | SSU ribosomal protein S27AE (rps27AE); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.634 |
SSO0432 | thi4 | SSO0432 | SSO0436 | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. | 0.565 |
SSO0433 | SSO0432 | SSO0433 | SSO0432 | O-sialoglycoprotein endopeptidase; Protein modification. | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.861 |
SSO0433 | kae1 | SSO0433 | SSO0434 | O-sialoglycoprotein endopeptidase; Protein modification. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | 0.993 |
SSO0433 | rps24E | SSO0433 | SSO0435 | O-sialoglycoprotein endopeptidase; Protein modification. | SSU ribosomal protein S24E (rps24E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.767 |
SSO0433 | rps27AE | SSO0433 | SSO5844 | O-sialoglycoprotein endopeptidase; Protein modification. | SSU ribosomal protein S27AE (rps27AE); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.634 |
SSO0433 | thi4 | SSO0433 | SSO0436 | O-sialoglycoprotein endopeptidase; Protein modification. | Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. | 0.565 |
kae1 | SSO0432 | SSO0434 | SSO0432 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.861 |
kae1 | SSO0433 | SSO0434 | SSO0433 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | O-sialoglycoprotein endopeptidase; Protein modification. | 0.993 |
kae1 | rps24E | SSO0434 | SSO0435 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | SSU ribosomal protein S24E (rps24E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.767 |
kae1 | rps27AE | SSO0434 | SSO5844 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | SSU ribosomal protein S27AE (rps27AE); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.634 |
kae1 | thi4 | SSO0434 | SSO0436 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. | 0.565 |
rps24E | SSO0432 | SSO0435 | SSO0432 | SSU ribosomal protein S24E (rps24E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS24 family. | HAM1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.652 |
rps24E | SSO0433 | SSO0435 | SSO0433 | SSU ribosomal protein S24E (rps24E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS24 family. | O-sialoglycoprotein endopeptidase; Protein modification. | 0.767 |
rps24E | kae1 | SSO0435 | SSO0434 | SSU ribosomal protein S24E (rps24E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS24 family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | 0.767 |
rps24E | rps27AE | SSO0435 | SSO5844 | SSU ribosomal protein S24E (rps24E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS24 family. | SSU ribosomal protein S27AE (rps27AE); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.991 |
rps24E | thi4 | SSO0435 | SSO0436 | SSU ribosomal protein S24E (rps24E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS24 family. | Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. | 0.721 |