STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
carACarbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. (367 aa)    
Predicted Functional Partners:
pyrC
Dihydroorotase (carbamoylaspartic dehydrase) (DHOase) (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
 0.999
pyrB
Aspartate carbamoyltransferase catalytic chain (ATCase) (pyrB); Pyrimidines.
 
 0.999
carB
Carbamoyl-phosphate synthase large subunit (carB); Amino Acid Biosynthesis, Pyrimidines.
 0.999
pyrD
Dihydroorotate dehydrogenase (dihydroorotate oxidase) (DHOdehase) (pyrD); Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
 
  
 0.996
pyrE
Orotate phosphoribosyltransferase (OPRT) (pyrE); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.996
pyrF
Orotidine 5'-phosphate decarboxylase (OMP decarboxylase) (OMPdcase) (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.994
SSO0612
Hypothetical protein.
  
  
 0.993
argG
Argininosuccinate synthetase (argG); Amino Acid Biosynthesis, Glutamate; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.992
purQ
Phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...]
  
 
 0.981
pyrI
Aspartate carbamoyltransferase regulatory chain (pyrI); Involved in allosteric regulation of aspartate carbamoyltransferase.
  
 
 0.980
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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