node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SSO0612 | carA | SSO0612 | SSO0640 | Hypothetical protein. | Carbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. | 0.993 |
SSO0612 | carB | SSO0612 | SSO0641 | Hypothetical protein. | Carbamoyl-phosphate synthase large subunit (carB); Amino Acid Biosynthesis, Pyrimidines. | 0.996 |
SSO0612 | pyrB | SSO0612 | SSO0614 | Hypothetical protein. | Aspartate carbamoyltransferase catalytic chain (ATCase) (pyrB); Pyrimidines. | 0.998 |
SSO0612 | pyrC | SSO0612 | SSO0611 | Hypothetical protein. | Dihydroorotase (carbamoylaspartic dehydrase) (DHOase) (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.989 |
SSO0612 | pyrD | SSO0612 | SSO0610 | Hypothetical protein. | Dihydroorotate dehydrogenase (dihydroorotate oxidase) (DHOdehase) (pyrD); Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.999 |
SSO0612 | pyrE | SSO0612 | SSO0615 | Hypothetical protein. | Orotate phosphoribosyltransferase (OPRT) (pyrE); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.997 |
SSO0612 | pyrF | SSO0612 | SSO0616 | Hypothetical protein. | Orotidine 5'-phosphate decarboxylase (OMP decarboxylase) (OMPdcase) (pyrF); Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.997 |
SSO0612 | pyrI | SSO0612 | SSO0613 | Hypothetical protein. | Aspartate carbamoyltransferase regulatory chain (pyrI); Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.901 |
argG | carA | SSO0638 | SSO0640 | Argininosuccinate synthetase (argG); Amino Acid Biosynthesis, Glutamate; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Carbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. | 0.992 |
argG | carB | SSO0638 | SSO0641 | Argininosuccinate synthetase (argG); Amino Acid Biosynthesis, Glutamate; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Carbamoyl-phosphate synthase large subunit (carB); Amino Acid Biosynthesis, Pyrimidines. | 0.999 |
argG | purQ | SSO0638 | SSO0628 | Argininosuccinate synthetase (argG); Amino Acid Biosynthesis, Glutamate; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...] | 0.503 |
argG | pyrB | SSO0638 | SSO0614 | Argininosuccinate synthetase (argG); Amino Acid Biosynthesis, Glutamate; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase catalytic chain (ATCase) (pyrB); Pyrimidines. | 0.918 |
argG | pyrI | SSO0638 | SSO0613 | Argininosuccinate synthetase (argG); Amino Acid Biosynthesis, Glutamate; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase regulatory chain (pyrI); Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.901 |
carA | SSO0612 | SSO0640 | SSO0612 | Carbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. | Hypothetical protein. | 0.993 |
carA | argG | SSO0640 | SSO0638 | Carbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. | Argininosuccinate synthetase (argG); Amino Acid Biosynthesis, Glutamate; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.992 |
carA | carB | SSO0640 | SSO0641 | Carbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. | Carbamoyl-phosphate synthase large subunit (carB); Amino Acid Biosynthesis, Pyrimidines. | 0.999 |
carA | purQ | SSO0640 | SSO0628 | Carbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. | Phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...] | 0.981 |
carA | pyrB | SSO0640 | SSO0614 | Carbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. | Aspartate carbamoyltransferase catalytic chain (ATCase) (pyrB); Pyrimidines. | 0.999 |
carA | pyrC | SSO0640 | SSO0611 | Carbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. | Dihydroorotase (carbamoylaspartic dehydrase) (DHOase) (pyrC); Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.999 |
carA | pyrD | SSO0640 | SSO0610 | Carbamoyl-phosphate synthase, small subunit (carA); Amino Acid Biosynthesis; Belongs to the CarA family. | Dihydroorotate dehydrogenase (dihydroorotate oxidase) (DHOdehase) (pyrD); Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.996 |