STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioRBiotin--(acetyl-CoA carboxylase) synthetase (bioR); Cofactor Biosynthesis, Biotin. (233 aa)    
Predicted Functional Partners:
accC
Biotin carboxylase a subunit of propionyl-CoA carboxylase (accC); Lipid metabolism.
 
 0.995
ppcB
Propionyl-CoA carboxylase beta subunit (ppcB); Lipid metabolism.
 
 
 0.989
SSO2464
Biotin carboxyl carrier protein of propionyl-CoA carboxylase beta subunit; Lipid metabolism.
 
 
 
 0.945
bioB
Biotin synthase (bioB); Cofactor Biosynthesis, Biotin.
     
  0.900
SSO0664
SUA5 related conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
 
     0.875
NuoB
NADH dehydrogenase subunit B (NuoB); Energy Metabolism, Electron transport; Belongs to the complex I 20 kDa subunit family.
  
    0.739
nadE
NH(3+) dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
  
 0.688
ndk
Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
     
 0.614
panB
Ketopantoate hydroxymethyltransferase (panB); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
  
 0.593
purB
Adenylosuccinate lyase (adenylosuccinase)(ASL) (purB); Purines; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.576
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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