STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmKCytidylate kinase (cmK); Pyrimidines. (189 aa)    
Predicted Functional Partners:
rpl34E
LSU ribosomal protein L34E (rpl34E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eL34 family.
  
    0.970
rpl24AB
LSU ribosomal protein L24AB (rpl24AB); One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
 
    0.965
rpl14AB
LSU ribosomal protein L14AB (rpl14AB); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
  
    0.959
rps4E
SSU ribosomal protein S4E (rps4E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS4 family.
  
    0.958
rpl5AB
LSU ribosomal protein L5AB (rpl5AB); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
    0.956
rps17AB
SSU ribosomal protein S17AB (rps17AB); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
    0.947
rps8AB
SSU ribosomal protein S8AB (rps8AB); One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
  
    0.944
rpl32E
LSU ribosomal protein L32E (rpl32E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eL32 family.
  
    0.937
rpl22AB
LSU ribosomal protein L22AB (rpl22AB); This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
    0.936
rpl4AE
LSU ribosomal protein L4AE (rpl4AE); One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
  
    0.934
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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