STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erm/ksgArRNA adenine N-6-methyltransferase (erm/ksgA); Multiple homologs; Translation, RNA modification; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (194 aa)    
Predicted Functional Partners:
rps3AE
SSU ribosomal protein S3AE (rps3AE); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
 0.959
nep1
Conserved hypothetical protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
 
 0.949
rps4AB
SSU ribosomal protein S4AB (rps4AB); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
 0.928
SSO2218
Conserved hypothetical protein; Similarity with PH0709, PAB0882, MTH1862, MJ1474, AF0385.
   
 
 0.928
rps10AB
SSU ribosomal protein S10AB (rps10AB); Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
  
 
 0.924
rtcA
RNA 3' terminal phosphate cyclase (RNA 3' phosphate cyclase) (RNA cyclase) (rtcA); Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
  
   0.921
rpS7AB
SSU ribosomal protein S7AB (rpS7AB); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.919
rps19AB
SSU ribosomal protein S19AB (rps19AB); Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
 
 
 0.912
rps17AB
SSU ribosomal protein S17AB (rps17AB); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
  
 
 0.909
rps2AB
SSU ribosomal protein S2AB (rps2AB); Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.908
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.