node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SSO0276 | rpl37E | SSO0276 | SSO6453 | Hypothetical protein. | LSU ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. | 0.602 |
SSO0276 | snRNP-1 | SSO0276 | SSO5410 | Hypothetical protein. | Small nuclear riboprotein protein (snRNP-1); Transcription, RNA modification. | 0.870 |
SSO0276 | snRNP-2 | SSO0276 | SSO6454 | Hypothetical protein. | Small nuclear riboprotein protein (snRNP-2); Transcription, RNA modification. | 0.870 |
SSO0276 | speE | SSO0276 | SSO0757 | Hypothetical protein. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to various amine acceptors such as putrescine (1,4-diaminobutane), 1,3-diaminopropane, sym- norspermidine and spermidine. The biosynthesis of caldopentamine from norspermine has been also ob [...] | 0.816 |
SpeD | speE | SSO0536 | SSO0757 | Conserved hypothetical protein; Specifically catalyzes the decarboxylation of L-arginine to agmatine. Is also able to decarboxylate L-canavanine, although less efficiently. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to various amine acceptors such as putrescine (1,4-diaminobutane), 1,3-diaminopropane, sym- norspermidine and spermidine. The biosynthesis of caldopentamine from norspermine has been also ob [...] | 0.995 |
SpeD | speH | SSO0536 | SSO0585 | Conserved hypothetical protein; Specifically catalyzes the decarboxylation of L-arginine to agmatine. Is also able to decarboxylate L-canavanine, although less efficiently. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | Conserved hypothetical protein; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine. Has no arginine decarboxylase (ArgDC) activity. Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. | 0.904 |
mtaP | mtaP-2 | SSO2343 | SSO2706 | 5'-methylthioadenosine phosphorylase (mtaP); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 5'-methylthioadenosine phosphorylase (mtaP); Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. Cleaves inosine, guanosine, and adenosine with a better efficiency than MTA. | 0.973 |
mtaP | speE | SSO2343 | SSO0757 | 5'-methylthioadenosine phosphorylase (mtaP); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to various amine acceptors such as putrescine (1,4-diaminobutane), 1,3-diaminopropane, sym- norspermidine and spermidine. The biosynthesis of caldopentamine from norspermine has been also ob [...] | 0.945 |
mtaP-2 | mtaP | SSO2706 | SSO2343 | 5'-methylthioadenosine phosphorylase (mtaP); Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. Cleaves inosine, guanosine, and adenosine with a better efficiency than MTA. | 5'-methylthioadenosine phosphorylase (mtaP); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.973 |
mtaP-2 | speE | SSO2706 | SSO0757 | 5'-methylthioadenosine phosphorylase (mtaP); Cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. Cleaves inosine, guanosine, and adenosine with a better efficiency than MTA. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to various amine acceptors such as putrescine (1,4-diaminobutane), 1,3-diaminopropane, sym- norspermidine and spermidine. The biosynthesis of caldopentamine from norspermine has been also ob [...] | 0.900 |
rpl37E | SSO0276 | SSO6453 | SSO0276 | LSU ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. | Hypothetical protein. | 0.602 |
rpl37E | snRNP-1 | SSO6453 | SSO5410 | LSU ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. | Small nuclear riboprotein protein (snRNP-1); Transcription, RNA modification. | 0.855 |
rpl37E | snRNP-2 | SSO6453 | SSO6454 | LSU ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. | Small nuclear riboprotein protein (snRNP-2); Transcription, RNA modification. | 0.972 |
rpl37E | speE | SSO6453 | SSO0757 | LSU ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to various amine acceptors such as putrescine (1,4-diaminobutane), 1,3-diaminopropane, sym- norspermidine and spermidine. The biosynthesis of caldopentamine from norspermine has been also ob [...] | 0.863 |
snRNP-1 | SSO0276 | SSO5410 | SSO0276 | Small nuclear riboprotein protein (snRNP-1); Transcription, RNA modification. | Hypothetical protein. | 0.870 |
snRNP-1 | rpl37E | SSO5410 | SSO6453 | Small nuclear riboprotein protein (snRNP-1); Transcription, RNA modification. | LSU ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. | 0.855 |
snRNP-1 | speE | SSO5410 | SSO0757 | Small nuclear riboprotein protein (snRNP-1); Transcription, RNA modification. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to various amine acceptors such as putrescine (1,4-diaminobutane), 1,3-diaminopropane, sym- norspermidine and spermidine. The biosynthesis of caldopentamine from norspermine has been also ob [...] | 0.817 |
snRNP-2 | SSO0276 | SSO6454 | SSO0276 | Small nuclear riboprotein protein (snRNP-2); Transcription, RNA modification. | Hypothetical protein. | 0.870 |
snRNP-2 | rpl37E | SSO6454 | SSO6453 | Small nuclear riboprotein protein (snRNP-2); Transcription, RNA modification. | LSU ribosomal protein L37E (rpl37E); Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. | 0.972 |
snRNP-2 | speE | SSO6454 | SSO0757 | Small nuclear riboprotein protein (snRNP-2); Transcription, RNA modification. | Spermidine synthase; Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high- temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to various amine acceptors such as putrescine (1,4-diaminobutane), 1,3-diaminopropane, sym- norspermidine and spermidine. The biosynthesis of caldopentamine from norspermine has been also ob [...] | 0.956 |