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carS protein (Sulfolobus solfataricus) - STRING interaction network
"carS" - CDP-archaeol synthase in Sulfolobus solfataricus
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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carSCDP-archaeol synthase; Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids (166 aa)    
Predicted Functional Partners:
ubiA-2
Digeranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. Cannot use other prenyl donors, i.e. farnesyl diphosphate (FPP) and phytyl diphosphate. Moreover, 4-hydroxybenzoate, 1,4-dihydroxy 2-naphthoate, homogentisate, and alpha-glycerophosphate do not function as prenyl acceptor substrates (282 aa)
 
   
  0.995
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily (314 aa)
 
   
  0.963
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family (227 aa)
 
   
  0.956
radA-like
DNA repair protein radA homolog (RadA-like); Bacterial RadA-like (related to bacterial sequences); Replication and Repair (175 aa)
   
        0.919
SSO0775
annotation not available (109 aa)
              0.915
SSO2989
Diphosphomevalonate decarboxylase; Catalyzes the decarboxylation of mevalonate 5- diphosphate (MVAPP) to isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the diphosphomevalonate decarboxylase family (325 aa)
     
   
  0.900
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, putataive (PgsA); Lipid metabolism; Belongs to the CDP-alcohol phosphatidyltransferase class-I family (195 aa)
   
 
  0.888
SSO0064
annotation not available (241 aa)
 
     
  0.883
gldA
Glycerol-1-phosphate dehydrogenase [NAD(P)+]; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea; Belongs to the glycerol-1-phosphate dehydrogenase family (351 aa)
 
     
  0.861
SSO0259
Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids (255 aa)
   
     
  0.846
Your Current Organism:
Sulfolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Sulfolobus solfataricus, Sulfolobus solfataricus P2, Sulfolobus solfataricus str. P2, Sulfolobus solfataricus strain P2
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