STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thsAThermosome subunit alpha; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity (559 aa)    
Predicted Functional Partners:
tuF-1
Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
  
 
 0.863
thsB
Thermosome subunit beta; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity
  
 
 
0.809
sod
Superoxide dismutase [Fe]; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems
 
 
 0.798
atpA
V-type ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit
  
 
 0.769
bcp-2
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
  
 
 0.768
psmA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation
  
 
 0.737
rpoA1
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
 
 
 0.735
eiF5A
Translation initiation factor 5A; Functions by promoting the formation of the first peptide bond
 
 
 0.733
rpl10E
Translation, Ribosomal Proteins; Belongs to the universal ribosomal protein uL16 family
 
 
 0.727
rps17AB
30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
 
  
 0.723
Your Current Organism:
Sulfolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Sulfolobus solfataricus, Sulfolobus solfataricus P2, Sulfolobus solfataricus str. P2, Sulfolobus solfataricus strain P2
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