node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argS | gltX | SSO0857 | SSO0093 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | 0.984 |
argS | hisS | SSO0857 | SSO0279 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Histidyl-tRNA synthetase (hisS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.768 |
argS | ileS | SSO0857 | SSO0722 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Isoleucine-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.997 |
argS | leuS-1 | SSO0857 | SSO0504 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Leucyl-tRNA synthetase (leuS-1); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.962 |
argS | metS | SSO0857 | SSO0558 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Methionyl-tRNA synthetase (metS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. | 0.988 |
argS | pheS | SSO0857 | SSO0100 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phenylalanyl-tRNA synthetase alpha subunit (pheS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. | 0.919 |
argS | serS | SSO0857 | SSO0602 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.968 |
argS | thrS | SSO0857 | SSO2486 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Threonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr); unlike most archaea the editing function is found in a freestanding protein (ACQ980D1). In vitro when both subunits are present, or if the 2 subunits are fused, L-seryl-tRNA(Thr) is no longer produced, the 2 subunits edit incorrectly charged L-seryl- tRNA(Thr). Has no activity on correctly acylated L- seryl-tRNA(Ser) [...] | 0.889 |
argS | tyrS | SSO0857 | SSO0078 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Tyrosyl-tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. | 0.912 |
argS | valS | SSO0857 | SSO0899 | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | Valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.965 |
gltX | argS | SSO0093 | SSO0857 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Arginyl-tRNA synthetase (argS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.984 |
gltX | hisS | SSO0093 | SSO0279 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Histidyl-tRNA synthetase (hisS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.729 |
gltX | ileS | SSO0093 | SSO0722 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Isoleucine-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity); Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. | 0.966 |
gltX | leuS-1 | SSO0093 | SSO0504 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Leucyl-tRNA synthetase (leuS-1); Translation, Aminoacyl tRNA synthetases; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.959 |
gltX | metS | SSO0093 | SSO0558 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Methionyl-tRNA synthetase (metS); Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. | 0.935 |
gltX | pheS | SSO0093 | SSO0100 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Phenylalanyl-tRNA synthetase alpha subunit (pheS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. | 0.758 |
gltX | serS | SSO0093 | SSO0602 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Seryl-tRNA synthetase (serS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.825 |
gltX | thrS | SSO0093 | SSO2486 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Threonyl-tRNA synthetase (thrS); Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr); unlike most archaea the editing function is found in a freestanding protein (ACQ980D1). In vitro when both subunits are present, or if the 2 subunits are fused, L-seryl-tRNA(Thr) is no longer produced, the 2 subunits edit incorrectly charged L-seryl- tRNA(Thr). Has no activity on correctly acylated L- seryl-tRNA(Ser) [...] | 0.808 |
gltX | tyrS | SSO0093 | SSO0078 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Tyrosyl-tRNA synthetase (tyrS); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily. | 0.775 |
gltX | valS | SSO0093 | SSO0899 | Glutamyl-tRNA synthetase (gltX); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). | Valyl-tRNA synthetase (valS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.913 |