node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GcvT | gcvH1 | SSO0919 | SSO0920 | Aminomethyltransferase; Energy Metabolism. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
GcvT | gcvH2 | SSO0919 | SSO1061 | Aminomethyltransferase; Energy Metabolism. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.998 |
GcvT | gcvH3 | SSO0919 | SSO1105 | Aminomethyltransferase; Energy Metabolism. | Glycine cleavage system protein H, hypothetical; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.998 |
GcvT | gcvPA | SSO0919 | SSO0918 | Aminomethyltransferase; Energy Metabolism. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
GcvT | gcvPB | SSO0919 | SSO0917 | Aminomethyltransferase; Energy Metabolism. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.999 |
GcvT | glyA | SSO0919 | SSO0530 | Aminomethyltransferase; Energy Metabolism. | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with the modified folate sulfopterin serving as the one-carbon carrier. Cannot use tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of both allo-threonine and beta-phenylserine. | 0.999 |
GcvT | pdhD-1 | SSO0919 | SSO1123 | Aminomethyltransferase; Energy Metabolism. | Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.962 |
GcvT | pdhD-2 | SSO0919 | SSO1524 | Aminomethyltransferase; Energy Metabolism. | Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.962 |
GcvT | pdhD-3 | SSO0919 | SSO1565 | Aminomethyltransferase; Energy Metabolism. | Dihydrolipoamide dehydrogenase (pdhD-3); Highest hit with Thermoplasma; Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.964 |
GcvT | pdhD-4 | SSO0919 | SSO2559 | Aminomethyltransferase; Energy Metabolism. | Dihydrolipoamide dehydrogenase (pdhD-4); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.962 |
gcvH1 | GcvT | SSO0920 | SSO0919 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase; Energy Metabolism. | 0.999 |
gcvH1 | gcvH2 | SSO0920 | SSO1061 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.910 |
gcvH1 | gcvH3 | SSO0920 | SSO1105 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system protein H, hypothetical; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.917 |
gcvH1 | gcvPA | SSO0920 | SSO0918 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.995 |
gcvH1 | gcvPB | SSO0920 | SSO0917 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.998 |
gcvH1 | glyA | SSO0920 | SSO0530 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with the modified folate sulfopterin serving as the one-carbon carrier. Cannot use tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of both allo-threonine and beta-phenylserine. | 0.970 |
gcvH1 | pdhD-1 | SSO0920 | SSO1123 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.962 |
gcvH1 | pdhD-2 | SSO0920 | SSO1524 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.964 |
gcvH1 | pdhD-3 | SSO0920 | SSO1565 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase (pdhD-3); Highest hit with Thermoplasma; Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.961 |
gcvH1 | pdhD-4 | SSO0920 | SSO2559 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase (pdhD-4); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.963 |