STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prsRibose phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class III (archaeal) subfamily. (294 aa)    
Predicted Functional Partners:
pmM
Phosphomannomutase (pmM); Cell Envelope, Surface polysaccharides and lipopolysaccharides; Belongs to the phosphohexose mutase family.
 
 0.971
rbsK-1
Ribokinase (rbsK-1); Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.960
rpiA
Ribose 5-phosphate isomerase (rpiA); Energy Metabolism.
  
 
 0.956
pdhB-1
Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-1); Strong similarity to acetoin:DCPIP oxidoreductase-beta (acoB) gene from R. eutropha; Energy Metabolism, Dehydrogenases.
  
 0.955
pdhB-2
Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-2); Strong similarity to acetoin:DCPIP oxidoreductase-beta (acoB) gene from R. eutropha; Energy Metabolism, Dehydrogenases.
  
 0.955
rbsK-2
Ribokinase (rbsK-2); Energy Metabolism.
  
 0.939
purF-1
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 0.938
purF-2
Amidophosphoribosyltransferase; Purines; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.938
pdhC
Dihydrolipoamide S-acetyltransferase, amino-end (pdhC); Probable frameshift with SSO1530; Energy Metabolism.
  
 0.929
pdhC-2
Dihydrolipoamide S-acetyltransferase, carboxy-end (pdhC); Probable frameshift with SSO1529; Energy Metabolism.
  
 0.929
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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