STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lplA-like1Lipoate protein ligase A, hypothetical (lplA-like1); Cofactor Biosynthesis. (279 aa)    
Predicted Functional Partners:
gcvH2
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.959
lipA
Lipoic acid synthetase (lipoate synthase) (lipA); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the radical SAM superfamily. Lipoyl synthase family.
  
 
 0.931
lplA-1
Lipoate-protein ligase A (lplA-1); Cofactor Biosynthesis.
  
  
 
0.923
lplA-like2
Lipoate protein ligase A, hypothetical (lplA-like2); Cofactor Biosynthesis.
  
  
 
0.915
pdhC-2
Dihydrolipoamide S-acetyltransferase, carboxy-end (pdhC); Probable frameshift with SSO1529; Energy Metabolism.
 
 0.819
pdhC
Dihydrolipoamide S-acetyltransferase, amino-end (pdhC); Probable frameshift with SSO1530; Energy Metabolism.
 
 0.801
gcvH1
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.768
gcvH3
Glycine cleavage system protein H, hypothetical; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.768
pdhB-1
Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-1); Strong similarity to acetoin:DCPIP oxidoreductase-beta (acoB) gene from R. eutropha; Energy Metabolism, Dehydrogenases.
 
 
 0.752
pdhB-2
Pyruvate dehydrogenase, beta subunit (lipoamide). (pdhB-2); Strong similarity to acetoin:DCPIP oxidoreductase-beta (acoB) gene from R. eutropha; Energy Metabolism, Dehydrogenases.
 
 
 0.751
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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