STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gctAGlutaconate CoA-transferase, subunit A (gctA); Energy Metabolism. (268 aa)    
Predicted Functional Partners:
gctB
Glutaconate CoA-transferase, subunit B (gctB); Energy Metabolism.
 0.999
gatA-3
Glutamyl-tRNA amidotransferase, subunit A (gatA-3); Enantioselective, active on 2- to 6-carbon aliphatic amides and on many aromatic amides; Belongs to the amidase family.
    
  0.901
pcaC
4-carboxymucolactone decarboxylase (pcaC); Amino Acid Biosynthesis, Aromatic amino acids.
 
  
 0.733
ppcB
Propionyl-CoA carboxylase beta subunit (ppcB); Lipid metabolism.
  
  
 0.636
SSO1082
Transcriptional regulator, marR family, putative; Transcription, RNA polymerase and transcription factors.
     
 0.597
purB
Adenylosuccinate lyase (adenylosuccinase)(ASL) (purB); Purines; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.565
citE
Citryl-CoA lyase beta subunit homolog (citE); Energy Metabolism.
     
 0.535
leuA-1
2-isopropylmalate synthase, putative (leuA-1); Amino Acid Biosynthesis, Pyruvate; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 0.507
leuA-2
2-isopropylmalate synthase (leuA-2); Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway. Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
  
  
 0.507
leuA-3
2-isopropylmalate synthase, putative (leuA-3); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Carries out the first step of the leucine biosynthesis pathway.
  
  
 0.507
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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