STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpB-likeTryptophan synthase beta chain, hypothetical (trpB-like); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (429 aa)    
Predicted Functional Partners:
trpC
Indole-3-glycerol phosphate synthase (trpC); Amino Acid Biosynthesis, Aromatic amino acids.
 
 
 0.993
trpA
Tryptophan synthase alpha chain (trpA); The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
 0.986
tdcB
Threonine dehydratase catabolic (threonine deaminase) (tdcB); Amino Acid Biosynthesis, Aspartate.
    
 0.910
glyA
Serine hydroxymethyltransferase (glyA); Catalyzes the reversible interconversion of serine and glycine with the modified folate sulfopterin serving as the one-carbon carrier. Cannot use tetrahydrofolate (THF or H4PteGlu) as the pteridine substrate. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. Thus, is able to catalyze the cleavage of both allo-threonine and beta-phenylserine.
    
  0.908
trpB
Tryptophan synthase beta chain (trpB); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
  
0.905
SSO1143
Conserved hypothetical protein.
       0.548
SSO1144
ABC transporter, ATP binding protein; Transport.
       0.548
SSO1146
Hypothetical protein; Putative permease.
       0.426
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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