STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gdhA-1NAD specific glutamate dehydrogenase (gdhA-1); Amino Acid Biosynthesis, Glutamate; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (419 aa)    
Predicted Functional Partners:
idh
Isocitrate dehydrogenase, probable (idh); Energy Metabolism, Tri-Carboxylic Acid Cycle.
  
 0.939
SSO0031
Conserved hypothetical protein.
  
 
 0.938
aspB-2
Aspartate aminotransferase (aspB-2); Amino Acid Biosynthesis, Aspartate.
  
 
 0.924
glnA-1
Glutamine synthetase (glutamate ammonia ligase) (GS). (glnA-1); Amino Acid Biosynthesis, Glutamate.
  
 
 0.916
glnA-2
Glutamine synthetase (glutamate ammonia ligase) (GS). (glnA-2); Amino Acid Biosynthesis, Glutamate; Belongs to the glutamine synthetase family.
  
 
 0.916
purQ
Phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (purQ); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...]
    
  0.907
gltA
Citrate synthase; Energy Metabolism; Belongs to the citrate synthase family.
  
 0.904
rimK-2
Translation, Protein modification.
    
 0.902
gdhA-2
NAD specific glutamate dehydrogenase (gdhA-2); Amino Acid Biosynthesis, Glutamate; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
0.901
gdhA-3
NAD specific glutamate dehydrogenase (gdhA-3); Amino Acid Biosynthesis, Glutamate; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
  
0.901
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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