node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adh-2 | araD | SSO0764 | SSO3124 | Alcohol dehydrogenase (Zn containing) (adh-2); Energy Metabolism. | Mandelate racemase /muconate lactonizing enzyme related protein (MR/MLE); Catalyzes the dehydration of D-arabinonate to 2-keto-3-deoxy- D-arabinonate. Participates in a pentose oxidation pathway that converts D-arabinonate to 2-oxoglutarate. | 0.535 |
adh-2 | mdlC | SSO0764 | SSO1647 | Alcohol dehydrogenase (Zn containing) (adh-2); Energy Metabolism. | Benzoylformate decarboxylase (mdlC); Amino Acid Biosynthesis, Aromatic amino acids; Belongs to the TPP enzyme family. | 0.795 |
araD | adh-2 | SSO3124 | SSO0764 | Mandelate racemase /muconate lactonizing enzyme related protein (MR/MLE); Catalyzes the dehydration of D-arabinonate to 2-keto-3-deoxy- D-arabinonate. Participates in a pentose oxidation pathway that converts D-arabinonate to 2-oxoglutarate. | Alcohol dehydrogenase (Zn containing) (adh-2); Energy Metabolism. | 0.535 |
araD | ilvD | SSO3124 | SSO3107 | Mandelate racemase /muconate lactonizing enzyme related protein (MR/MLE); Catalyzes the dehydration of D-arabinonate to 2-keto-3-deoxy- D-arabinonate. Participates in a pentose oxidation pathway that converts D-arabinonate to 2-oxoglutarate. | Dihydroxy-acid dehydratase (ilvD); Amino Acid Biosynthesis; Belongs to the IlvD/Edd family. | 0.671 |
araD | mdlC | SSO3124 | SSO1647 | Mandelate racemase /muconate lactonizing enzyme related protein (MR/MLE); Catalyzes the dehydration of D-arabinonate to 2-keto-3-deoxy- D-arabinonate. Participates in a pentose oxidation pathway that converts D-arabinonate to 2-oxoglutarate. | Benzoylformate decarboxylase (mdlC); Amino Acid Biosynthesis, Aromatic amino acids; Belongs to the TPP enzyme family. | 0.809 |
ilvB-1 | ilvB-2 | SSO0170 | SSO0579 | Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate. | Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. | 0.665 |
ilvB-1 | ilvB-4 | SSO0170 | SSO2774 | Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate. | Acetolactate synthase large subunit homolog (ilvB-4); Amino Acid Biosynthesis, Pyruvate; Belongs to the TPP enzyme family. | 0.661 |
ilvB-1 | ilvB-6 | SSO0170 | SSO3210 | Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate. | Acetolactate synthase large subunit homolog (ilvB-6); Amino Acid Biosynthesis, Pyruvate. | 0.849 |
ilvB-1 | ilvC-1 | SSO0170 | SSO0576 | Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate. | Ketol-acid reductoisomerase (ilvC-1); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.810 |
ilvB-1 | ilvC-2 | SSO0170 | SSO1322 | Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate. | Ketol-acid reductoisomerase (ilvC-2); Amino Acid Biosynthesis, Pyruvate; Belongs to the ketol-acid reductoisomerase family. | 0.805 |
ilvB-1 | ilvD | SSO0170 | SSO3107 | Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate. | Dihydroxy-acid dehydratase (ilvD); Amino Acid Biosynthesis; Belongs to the IlvD/Edd family. | 0.801 |
ilvB-1 | leuA-3 | SSO0170 | SSO2407 | Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate. | 2-isopropylmalate synthase, putative (leuA-3); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Carries out the first step of the leucine biosynthesis pathway. | 0.509 |
ilvB-1 | mdlC | SSO0170 | SSO1647 | Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate. | Benzoylformate decarboxylase (mdlC); Amino Acid Biosynthesis, Aromatic amino acids; Belongs to the TPP enzyme family. | 0.674 |
ilvB-2 | ilvB-1 | SSO0579 | SSO0170 | Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. | Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate. | 0.665 |
ilvB-2 | ilvB-4 | SSO0579 | SSO2774 | Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. | Acetolactate synthase large subunit homolog (ilvB-4); Amino Acid Biosynthesis, Pyruvate; Belongs to the TPP enzyme family. | 0.629 |
ilvB-2 | ilvB-6 | SSO0579 | SSO3210 | Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. | Acetolactate synthase large subunit homolog (ilvB-6); Amino Acid Biosynthesis, Pyruvate. | 0.927 |
ilvB-2 | ilvC-1 | SSO0579 | SSO0576 | Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. | Ketol-acid reductoisomerase (ilvC-1); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.993 |
ilvB-2 | ilvC-2 | SSO0579 | SSO1322 | Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. | Ketol-acid reductoisomerase (ilvC-2); Amino Acid Biosynthesis, Pyruvate; Belongs to the ketol-acid reductoisomerase family. | 0.840 |
ilvB-2 | ilvD | SSO0579 | SSO3107 | Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. | Dihydroxy-acid dehydratase (ilvD); Amino Acid Biosynthesis; Belongs to the IlvD/Edd family. | 0.914 |
ilvB-2 | leuA-3 | SSO0579 | SSO2407 | Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate. | 2-isopropylmalate synthase, putative (leuA-3); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Carries out the first step of the leucine biosynthesis pathway. | 0.903 |